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Fig. 6 | Cancer Nanotechnology

Fig. 6

From: Nanoparticle delivery of si-Notch1 modulates metabolic reprogramming to affect 5-FU resistance and cell pyroptosis in colorectal cancer

Fig. 6

PLGA NPs-delivered si-Notch1 reverses 5-FU resistance of CRC cells. A Relative expression of Notch1 in SW620-R and HCT8-R cells was detected by qRT-PCR. B The viability of SW620-R and HCT8-R cells was assessed by CCK-8 assay. C Apoptosis rates of SW620-R and HCT8-R cells were examined using flow cytometry analysis. D For calculate the half-maximal inhibitory concentration (IC50), the viability of SW620-R and HCT8-R cells was assessed by CCK-8 assay. **P < 0.01. ***P < 0.001

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