Advancing nanoparticles from the bench to the bedside: logistical issues
Interaction with man-made nanoparticles is becoming inescapable in the daily lives of people around the world. This has been enabled by the explosion of research in nanotechnology especially in medicinal and consumer products. This research has catalyzed the design of products with precisely engineered and highly robust functionalities with minimal toxicity. The next step is to advance these exciting new discoveries from the bench to the bedside. Here, there seems to be a bottleneck where very few nanotechnology products have successfully transitioned. Even among those that have moved to clinical testing, many have failed to demonstrate clear clinical benefit. This collection in Cancer Nanotechnology seeks to highlight strategies to overcome potential regulatory, societal, business and legal hurdles.
Topics include, but are not limited to:
- Challenges with scale-up and reproducibility
- Defining the regulatory path to clinical testing
- Legal and intellectual property issues
- Trends in business practice
- Government and regulatory science
Steven Curley, Christus Trinity Mother Frances, Texas, USA
Sunil Krishnan, MD Anderson, Texas, USA
Željka Krpetić, University of Salford, UK
30 September 2019
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