Fig. 5From: Evaluation of cytotoxicity and mechanism of apoptosis of doxorubicin using folate-decorated chitosan nanoparticles for targeted delivery to retinoblastomaInduction of apoptosis in Y-79 cell line by native DOX, DOX-CNPs, and DOX-CNP-FA. Cells were treated with 5 μM of native DOX and equivalent concentrations of DOX in NPs (DOX-CNP and DOX-CNP-FA) for 48 h and were then stained with Annexin V to access the apoptotic potential by flow cytometry. Results are representative of one of three independent experimentsBack to article page