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Fig. 9 | Cancer Nanotechnology

Fig. 9

From: Toxicogenomics of nanoparticulate delivery of etoposide: potential impact on nanotechnology in retinoblastoma therapy

Fig. 9

a Annexin-V FITC staining for apoptosis. Y-79 cells were treated with varying concentrations of drug in solution and in nanoformulation for 5 days. The apoptotic response was determined by Annexin-V FITC and PI staining procedure. b Analysis of DNA fragmentation by agarose gel electrophoresis. i Y-79 cells treated with native etoposide and NPs (0.0005 μg/ml) for 5 days. Control cells (lane 1), native etoposide (lane 2), NPs (lane 3) and DNA marker (lane 4). ii Y-79 cells treated with native etoposide (0.005 μg/ml) and NPs (0.005 μg/ml) for 5 days. Control cells (lane 1), native etoposide (lane 2), NPs (lane 3) and DNA marker (lane 4)

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