Fig. 10

a Display of microarray images of Y-79 cells treated with (0.0005 μg/ml) of native etoposide and (0.0005 μg/ml) NPs. Horizontal line represents the average expression of the individual genes modified. Red and green indicate the increased and decreased expression of genes. The figure represents one of the three replicates. b Functional grouping of upregulated genes (i) and downregulated genes (ii) in Y-79 cells treated with NPs. All the distinct gene identification were examined for their known biologic functions according to gene oncology convention and grouped in the respective functional category. The proportion of each functional category in the total number of selected identified genes (taken as 100%) is shown