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Fig. 2 | Cancer Nanotechnology

Fig. 2

From: Effect of liposomal celecoxib on proliferation of colon cancer cell and inhibition of DMBA-induced tumor in rat model

Fig. 2

a Hemolytic assay. In brief, red blood cells were collected by centrifugation of mice blood and resuspended in HEPES buffer saline (5% v/v). The cell suspension was added to HEPES buffer saline, 1% Triton X-100, free celecoxib, and empty and celecoxib-loaded liposomes, and incubated for 30 and 60 min at 37°C. After centrifugation, hemolytic activity was determined by measuring the absorbance of the supernatants at 570 nm. Control samples of 0% lysis (in HEPES buffer) and 100% lysis (in 1% Triton X-100) were used in the experiment. The bars indicate the mean±SD (n = 3). Significant difference is shown as **p < 0.05; ***p < 0.001 versus + control. b Antiproliferative activity of free celecoxib and liposomal celecoxib on HCT 15 cells. Each point in the graph indicates the mean±SD (n = 3)

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