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Table 2 The effect of liposomal celecoxib on antioxidant enzymes of liver in DMBA-induced cancer in rats

From: Effect of liposomal celecoxib on proliferation of colon cancer cell and inhibition of DMBA-induced tumor in rat model

Groups

Treatment groups

Superoxide dismutase

Lipid peroxidation

Group I

Normal control

3.45 ± 0.07*

0.79 ± 0.06*

Group II

Cancer control

1.27 ± 0.17

1.95 ± 0.27

Group III

Cancer + celecoxib

2.31 ± 0.29*

0.71 ± 0.06*

Group IV

Cancer + empty liposome

1.39 ± 0.37

1.77 ± 0.47*

Group V

Cancer + liposomal celecoxib

3.35 ± 0.21*

1.09 ± 0.08*

  1. Each value represents mean±SD of given number of animals (n = 4); comparison groups I, III, IV, and V with group II
  2. *P < 0.01, significant values