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Table 3 The effect of liposomal celecoxib on antioxidant enzymes of kidney in DMBA-induced cancer in rats

From: Effect of liposomal celecoxib on proliferation of colon cancer cell and inhibition of DMBA-induced tumor in rat model

Groups

Treatment

Superoxide dismutase

Lipid peroxidation

Group I

Normal control

1.55 ± 0.20*

1.70 ± 0.33*

Group II

Cancer control

0.69 ± 0.08

2.68 ± 0.24

Group III

Cancer + celecoxib

1.36 ± 0.12*

1.91 ± 0.40*

Group IV

Cancer + empty liposome

1.09 ± 0.20*

2.15 ± 0.24*

Group V

Cancer + liposomal celecoxib

1.18 ± 0.08*

1.69 ± 0.18*

  1. Each value represents mean±SD of given number of animals (n = 4); comparison groups I, III, IV, and V with group II
  2. *P < 0.01, significant values