Fig. 9

Confocal and fluorescence images of cancer cells treated with ORMOSILNs previously incubated with DNA labeled with ethidium monoazide (EMA). a Confocal bioimaging of cancer cells demonstrating expression of green fluorescent protein following in vitro administration. b Fluorescent image of nano-DNA complex stained with 4′-6-diamidino-2-phenylindole (DAPI). c 2-h incubation of nano-DNA complex with cells shows that the nanoparticles are present outside the cells. d Transformed into cells after 4-h incubation