Table 2 Box–Behnken experimental design with measured responses for exemestane-loaded cPCL NPs
Sr. No. | X 1 | X 2 | X 3 | Y1 (PDE, mean ± SD) | Y2 (PS, mean ± SD) |
|---|---|---|---|---|---|
1 | 0 | −1 | −1 | 56.32 ± 1.738 | 224.10 ± 7.213 |
2 | 0 | −1 | 1 | 73.36 ± 2.081 | 115.03 ± 3.595 |
3 | 0 | 1 | −1 | 23.94 ± 1.254 | 263.67 ± 4.549 |
4 | 0 | 1 | 1 | 72.89 ± 1.437 | 256.27 ± 5.387 |
5 | −1 | 0 | −1 | 57.93 ± 1.728 | 284.77 ± 4.879 |
6 | −1 | 0 | 1 | 64.68 ± 1.921 | 185.00 ± 4.424 |
7 | 1 | 0 | −1 | 48.71 ± 0.713 | 302.63 ± 2.875 |
8 | 1 | 0 | 1 | 82.00 ± 1.101 | 212.40 ± 3.050 |
9 | −1 | −1 | 0 | 70.91 ± 1.788 | 185.93 ± 3.502 |
10 | −1 | 1 | 0 | 54.94 ± 1.806 | 340.43 ± 8.334 |
11 | 1 | −1 | 0 | 74.89 ± 2.644 | 235.80 ± 6.777 |
12 | 1 | 1 | 0 | 68.95 ± 3.235 | 350.03 ± 7.214 |
13 | 0 | 0 | 0 | 82.67 ± 1.310 | 207.40 ± 2.035 |