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Table 3 Model coefficients estimated by multiple regression analysis for PDE of exemestane-loaded cPCL NPs

From: Encapsulation of exemestane in polycaprolactone nanoparticles: optimization, characterization, and release kinetics

Factor

Coefficients

t stat

p value

Intercept

82.67

13.5711

0.0009*

X 1

3.2596

1.5135

0.2274

X 2

−6.8440

−3.1777

0.0482*

X 3

13.2531

6.1536

0.0086*

X 1 X 2

2.5067

0.8230

0.4708

X 1 X 3

6.6334

2.1779

0.1176

X 2 X 3

7.9769

2.6190

0.0491*

X 1 2

−4.2709

−1.0600

0.3669

X 2 2

−10.9755

−2.7240

0.0423*

X 3 2

−15.0662

−3.7392

0.0334*

  1. *p < 0.05, significance level