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Fig. 7 | Cancer Nanotechnology

Fig. 7

From: Surface modification of cobalt oxide nanoparticles using phosphonomethyl iminodiacetic acid followed by folic acid: a biocompatible vehicle for targeted anticancer drug delivery

Fig. 7

DOX-FA-PMIDA-CoO NP-induced cellular apoptosis analysis in KB and KG1a cell lines by flow cytometry using propidium iodide. Here, a (KB cells) = control, b and c = KB cell + 10 and 25 μg/ml DOX-FA-PMIDA-CoO, respectively, d and e = KB cells + 10 and 25 μg/ml MTX-FA-PMIDA-CoO, respectively; nanoparticles induced cellular apoptosis analysis KG1a cell lines by flow cytometry using propidium iodide. Here, f = control, g and h = KG1a cell + 10 and 25 μg/ml DOX-FA-PMIDA-CoO, respectively, i and j = KG1a cells + 10 and 25 μg/ml MTX-FA-PMIDA-CoO, respectively. Here, P1 = G0/G1 phase (apoptotic phase), P2 = S phase (synthesis phase), P3 = M phase

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