Table 1 MeST of the 9LGS bearing rats without irradiation, after MRT irradiation (i) only, (ii) in presence of DOTAREM® and (iii) in presence of particles (with the same quantity of gadolinium)
Median survival time (Days) | Number of rats | |
|---|---|---|
Without irradiation | 19 | 9 |
Only MRT | 44 | 15 |
MRT irradiation 20 minutes after injection of 56 μL of DOTAREM® ([Gd]3+ = 1 M) | 32 | 8 |
MRT irradiation 20 minutes after injection of 1.4 mL of DOTAREM® ( [Gd]3+ = 40 mM]) | 43 | 8 |
MRT irradiation 20 minutes after injection of 1.4 mL of AGuIX nanoparticles ( [Gd]3+ = 40 mM]) | 102.5 | 8 |