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Figure 2 | Cancer Nanotechnology

Figure 2

From: The role of mitochondrial function in gold nanoparticle mediated radiosensitisation

Figure 2

DNA damage analysis measured by immunofluorescent staining of 53BP1 foci for (A) MDA-MB-231, (B) DU145 and (C) T98G cells treated with 500 μg/ml of 1.9 nm gold nanoparticles (GNPs), 24 hours prior to irradiation with 225 kVp X-rays at a dose of 2 Gy. Cells were fixed, stained and foci scored at 1 hour and 24 hours post irradiation. For each of the experimental conditions, foci were scored in > 50 nuclei. Experiments were performed at least three times in triplicate, means are presented ± standard error of the mean. Statistical analysis was performed using a paired t-test with significant differences assumed at the level of *p = × 0.05.

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