Fig. 2

Functionalized mesoporous silica nanoparticles (MSN) are taken up by mouse bladder cancer cells. Flow cytometry for MB49 bladder cancer cells exposed to 100 μg/mL PEG–Gd₂O₃–TRITC–MSN. a MB49-Luc⁺ cells were used as negative controls for both GFP and TRITC. b MB49-GFP⁺ cells prior to labeling were 99.8 % GFP⁺/TRITC⁻. c After labeling, 69.6 % of the cells were found to be GFP⁺/TRITC⁺, with a range of levels of rhodamine fluorescence, indicating some cells picked up more MSN particles than others