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Fig. 1 | Cancer Nanotechnology

Fig. 1

From: Gold nanoparticle mediated combined cancer therapy

Fig. 1

Characterization and cellular accumulation of GNPs. a Transmission electron microscopy (TEM) image of GNPs used in this study. b Hyperspectral image of 10 nm diameter GNPs. Scale bar = 10 µm. c Reflectance spectra collected from few GNP clusters in the image (b). d UV–Vis Spectra of GNPs and GNP-RGDs measured 46 h post formulation. e Cellular accumulation of GNPs and GNP-RGDs in MDA-MB-231 cells. Data are mean ± S.D. for n = 3. *Represents statistically significant difference (unpaired t-test, p < 0.05). f, g Hyperspectral images of cells internalized with GNPs and GNP-RGDs, respectively. The bright dot-like structures are GNP clusters localized within cells. Scale bar = 10 µm

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