Skip to main content

Table 3 Concentration of metabolites and activity of enzymes in blood serum of rats treated with the polymeric nanocarrier (PNC) for 20 days

From: Comb-like PEG-containing polymeric composition as low toxic drug nanocarrier

  Control group PNC treated group, 20 days
Aspartate transaminase activity, µkat/l 0.648 ± 0.045 0.538 ± 0.042*
Alanine transaminase activity, µkat/l 0.518 ± 0.034 0.425 ± 0.041*
De Ritis coefficient 1.25 ± 0.05 1.27 ± 0.09
γ-Glutamyltransferase activity, µkat/l 0.285 ± 0.034 0.255 ± 0.21
Creatine phosphokinase activity, µkat/l 2.31 ± 0.02 1.94 ± 0.05*
Alkaline phosphatase activity, µkat/l 2.58 ± 0.34 4.01 ± 0.28*
Lactate dehydrogenase activity, µkat/l 5.48 ± 0.12 3.69 ± 0.07*
α-Amylase activity, µkat/l 2.01 ± 0.09 2.36 ± 0.13
Total protein, g/l 76.5 ± 3.5 67.5 ± 3.2
Glucose, mmol/l 5.18 ± 0.89 6.09 ± 0.78
Urea, mmol/l 4.3 ± 0.2 5.1 ± 0.3
Creatinine, μmol/l 82.5 ± 4.1 70.7 ± 2.9*
Calcium cation, mmol/l 2.50 ± 0.34 3.22 ± 0.51
Iron cation, μmol/l 42.4 ± 2.1 42.5 ± 3.2
Sodium cation, mmol/l 127.5 ± 14.5 141.0 ± 9.8
Chloride anion, mmol/l 111.1 ± 4.9 119.8 ± 12.8
  1. * P ≤ 0.05