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Fig. 4 | Cancer Nanotechnology

Fig. 4

From: Importance of radiolytic reactions during high-LET irradiation modalities: LET effect, role of O2 and radiosensitization by nanoparticles

Fig. 4

Superoxide G-values as a function of LET. Black lines are provided from experimental irradiation by varying ions energy and their track-average LET in sample (LaVerne and Schuler 1987). Red lines are Monte Carlo simulations accounting for multi-ionization process (Gervais et al. 2005, 2006). Blue symbols are results of experiments using high energy ions providing almost constant LET in sample which correspond to short track segment before the Bragg peak (Baldacchino et al. 1998a, b). Kr result in blue is not published yet. Blue-tagged region is the area of the LET value in Bragg peak of 1 GeV-Carbon ions in which expected G-value of superoxide is about 0.2 × 10−7 mol J−1. The dotted line is guide for the eyes: it interpolates the G-values at lowest LET values of each C, Ne and Ni ions. These LET values are rather track segment LET values which are easier to compare with blue symbols

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