Table 1 Physicochemical parameters of the docetaxel-loaded and fluorescein diacetate-loaded PLGA nanoparticles
Sample | Z-average size, nm | Zeta potential, mV | Polydispersity index (PdI) | The content of docetaxel (1) or fluorescein diacetate (2) in the sample, % |
|---|---|---|---|---|
NP–Doc | 231.2 ± 4.6 | − 4.88 ± 0.41 | 0.091 ± 0.09 | 2.32 ± 0.07 (1) |
F–NP–Doc | 227.6 ± 5.9 | − 3.75 ± 0.29 | 0.068 ± 0.015 | 3.13 ± 0.10 (1) |
F–NP–FDA | 263.1 ± 6.2 | − 6.85 ± 0.24 | 0.075 ± 0.020 | 0.141 ± 0.009 (2) |