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Table 3 The cytostatic activity of F–NP–Doc versus free docetaxel expressed as IC50 value

From: In vitro anticancer activity of folate-modified docetaxel-loaded PLGA nanoparticles against drug-sensitive and multidrug-resistant cancer cells

Incubation time, h IC50, nM
Doc F–NP–Doc
24 21.2 ± 2.0 9.3 ± 1.3
48 3.5 ± 0.4 2.5 ± 0.3
72 1.8 ± 0.2 1.0 ± 0.1
  1. HeLa cells were incubated with F–NP–Doc and docetaxel for 24, 48 and 72 h. Cell survival was assessed using the SRB assay