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Table 4 The cytostatic activity of F–NP–Doc and free docetaxel against cancer cells expressed as IC50 value ± SE

From: In vitro anticancer activity of folate-modified docetaxel-loaded PLGA nanoparticles against drug-sensitive and multidrug-resistant cancer cells

Drug

Cells

HeLa

MCF7

MCF7R

MDA-MB-231

SKOV3

Ca755

LECH

Docetaxel

2.9 ± 0.4

7.7 ± 1.2

166 ± 15.3

0.5 ± 0.03

3.2 ± 0.4

9.7 ± 2.6

2.2 ± 1.9

F–NP–Doc

1.2 ± 0.3

4.9 ± 0.6

65 ± 8.3

1.8 ± 0.6

2.0 ± 0.4

5.6 ± 0.7

11.2 ± 2.2

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Cancer Nanotechnology

ISSN: 1868-6966

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