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Table 4 The cytostatic activity of F–NP–Doc and free docetaxel against cancer cells expressed as IC50 value ± SE

From: In vitro anticancer activity of folate-modified docetaxel-loaded PLGA nanoparticles against drug-sensitive and multidrug-resistant cancer cells

Drug Cells
HeLa MCF7 MCF7R MDA-MB-231 SKOV3 Ca755 LECH
Docetaxel 2.9 ± 0.4 7.7 ± 1.2 166 ± 15.3 0.5 ± 0.03 3.2 ± 0.4 9.7 ± 2.6 2.2 ± 1.9
F–NP–Doc 1.2 ± 0.3 4.9 ± 0.6 65 ± 8.3 1.8 ± 0.6 2.0 ± 0.4 5.6 ± 0.7 11.2 ± 2.2