| HDF-p53 | HDF-p27 | HDF-BAX | HDF-BCL2 | HDF-CASP3 | MDA-p53 | MDA-p27 | MDA-BAX | MDA-BCL2 | MDA-CASP3 | SKBR3-p53 | SKBR3-p27 | SKBR3-BAX | SKBR3-BCL2 | SKBR3-CASP3 | T47D-p53 | T47D-p27 | T47D-BAX | T47D-BCL2 | T47D-CASP3 | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HDF-p53 | Correlation coefficient | 1.000 | 0.714 | 0.194 | 0.278 | 0.561 | 0.917 | 0.576 | − 0.421 | 0.993 | 0.894 | − 0.865 | − 0.919 | − 0.945 | − 0.860 | 0.706 | − 0.979 | 0.054 | 0.516 | − 0.943 | − 0.538 |
Significance (2-tailed) | 0.000 | 0.494 | 0.876 | 0.821 | 0.621 | 0.261 | 0.609 | 0.723 | 0.075 | 0.296 | 0.335 | 0.258 | 0.211 | 0.341 | 0.501 | 0.130 | 0.966 | 0.655 | 0.216 | 0.638 | |
HDF-p27 | Correlation coefficient | 0.714 | 1.000 | − 0.549 | − 0.475 | 0.980 | 0.933 | 0.984 | − 0.936 | 0.791 | 0.952 | − 0.969 | − 0.932 | − 0.903 | − 0.971 | 0.007 | − 0.557 | 0.738 | 0.968 | − 0.906 | − 0.974 |
Significance (2-tailed) | 0.494 | 0.000 | 0.630 | 0.685 | 0.127 | 0.234 | 0.115 | 0.229 | 0.419 | 0.198 | 0.159 | 0.237 | 0.283 | 0.153 | 0.995 | 0.624 | 0.472 | 0.161 | 0.279 | 0.144 | |
HDF-BAX | Correlation coefficient | 0.194 | − 0.549 | 1.000 | 0.996 | − 0.703 | − 0.212 | − 0.690 | 0.808 | 0.077 | − 0.267 | 0.325 | 0.208 | 0.136 | 0.334 | 0.832 | − 0.389 | − 0.969 | − 0.740 | 0.143 | 0.723 |
Significance (2-tailed) | 0.876 | 0.630 | 0.000 | 0.055* | 0.503 | 0.864 | 0.515 | 0.401 | 0.951 | 0.828 | 0.789 | 0.867 | 0.913 | 0.783 | 0.374 | 0.746 | 0.159 | 0.470 | 0.909 | 0.486 | |
HDF-BCL2 | Correlation coefficient | 0.278 | − 0.475 | 0.996 | 1.000 | − 0.640 | − 0.128 | − 0.625 | 0.755 | 0.162 | − 0.183 | 0.242 | 0.123 | 0.051 | 0.252 | 0.876 | − 0.467 | − 0.944 | − 0.680 | 0.057 | 0.661 |
Significance (2-tailed) | 0.821 | 0.685 | 0.055* | 0.000 | 0.558 | 0.918 | 0.570 | 0.456 | 0.896 | 0.883 | 0.844 | 0.921 | 0.968 | 0.838 | 0.320 | 0.691 | 0.213 | 0.524 | 0.963 | 0.541 | |
HDF-CASP3 | Correlation coefficient | 0.561 | 0.980 | − 0.703 | − 0.640 | 1.000 | 0.844 | 1.000 | − 0.987 | 0.655 | 0.873 | − 0.901 | − 0.841 | − 0.800 | − 0.905 | − 0.191 | − 0.381 | 0.857 | 0.999 | − 0.804 | − 1.000 |
Significance (2-tailed) | 0.621 | 0.127 | 0.503 | 0.558 | 0.000 | 0.360 | 0.012* | 0.102 | 0.546 | 0.325 | 0.286 | 0.363 | 0.410 | 0.280 | 0.878 | 0.751 | 0.345 | 0.034 | 0.405 | 0.017* | |
MDA-p53 | Correlation coefficient | 0.917 | 0.933 | − 0.212 | − 0.128 | 0.844 | 1.000 | 0.854 | − 0.747 | 0.958 | 0.998 | − 0.993 | − 1.000 | − 0.997 | − 0.992 | 0.366 | − 0.818 | 0.447 | 0.814 | − 0.997 | − 0.829 |
Significance (2-tailed) | 0.261 | 0.234 | 0.864 | 0.918 | 0.360 | 0.000 | 0.348 | 0.463 | 0.185 | 0.036* | 0.074 | 0.003** | 0.049* | 0.081 | 0.762 | 0.391 | 0.705 | 0.394 | 0.045 | 0.378 | |
MDA-p27 | Correlation coefficient | 0.576 | 0.984 | − 0.690 | − 0.625 | 1.000 | 0.854 | 1.000 | − 0.984 | 0.669 | 0.882 | − 0.909 | − 0.851 | − 0.811 | − 0.913 | − 0.172 | − 0.398 | 0.847 | 0.997 | − 0.815 | − 0.999 |
Significance (2-tailed) | 0.609 | 0.115 | 0.515 | 0.570 | 0.012* | 0.348 | 0.000 | 0.114 | 0.534 | 0.313 | 0.274 | 0.351 | 0.398 | 0.268 | 0.890 | 0.739 | 0.357 | 0.046 | 0.393 | 0.029* | |
MDA-BAX | Correlation coefficient | − 0.421 | − 0.936 | 0.808 | 0.755 | − 0.987 | − 0.747 | − 0.984 | 1.000 | − 0.525 | − 0.784 | 0.820 | 0.744 | 0.694 | 0.825 | 0.345 | 0.228 | − 0.928 | − 0.994 | 0.698 | 0.991 |
Significance (2-tailed) | 0.723 | 0.229 | 0.401 | 0.456 | 0.102 | 0.463 | 0.114 | 0.000 | 0.648 | 0.427 | 0.388 | 0.466 | 0.512 | 0.382 | 0.776 | 0.853 | 0.243 | 0.069 | 0.508 | 0.085 | |
MDA-BCL2 | Correlation coefficient | 0.993 | 0.791 | 0.077 | 0.162 | 0.655 | 0.958 | 0.669 | − 0.525 | 1.000 | 0.940 | − 0.918 | − 0.959 | − 0.977 | − 0.914 | 0.617 | − 0.948 | 0.171 | 0.614 | − 0.976 | − 0.634 |
Significance (2-tailed) | 0.075 | 0.419 | 0.951 | 0.896 | 0.546 | 0.185 | 0.534 | 0.648 | 0.000 | 0.221 | 0.260 | 0.182 | 0.136 | 0.266 | 0.576 | 0.205 | 0.890 | 0.579 | 0.140 | 0.563 | |
MDA-CASP3 | Correlation coefficient | 0.894 | 0.952 | − 0.267 | − 0.183 | 0.873 | 0.998 | 0.882 | − 0.784 | 0.940 | 1.000 | − 0.998 | − 0.998 | − 0.991 | − 0.998 | 0.313 | − 0.784 | 0.496 | 0.846 | − 0.992 | − 0.859 |
Significance (2-tailed) | 0.296 | 0.198 | 0.828 | 0.883 | 0.325 | 0.036 | 0.313 | 0.427 | 0.221 | 0.000 | 0.038 | 0.039 | 0.085 | 0.045 | 0.798 | 0.427 | 0.669 | 0.358 | 0.081 | 0.342 | |
SKBR3-p53 | Correlation coefficient | − 0.865 | − 0.969 | 0.325 | 0.242 | − 0.901 | − 0.993 | − 0.909 | 0.820 | − 0.918 | − 0.998 | 1.000 | 0.993 | 0.981 | 1.000 | − 0.255 | 0.745 | − 0.548 | − 0.876 | 0.982 | 0.888 |
Significance (2-tailed) | 0.335 | 0.159 | 0.789 | 0.844 | 0.286 | 0.074 | 0.274 | 0.388 | 0.260 | 0.038* | 0.000 | 0.077 | 0.124 | 0.006** | 0.836 | 0.465 | 0.631 | 0.320 | 0.119 | 0.304 | |
SKBR3-p27 | Correlation coefficient | − 0.919 | − 0.932 | 0.208 | 0.123 | − 0.841 | − 1.000 | − 0.851 | 0.744 | − 0.959 | − 0.998 | 0.993 | 1.000 | 0.997 | 0.991 | − 0.370 | 0.820 | − 0.442 | − 0.812 | 0.998 | 0.826 |
Significance (2-tailed) | 0.258 | 0.237 | 0.867 | 0.921 | 0.363 | 0.003** | 0.351 | 0.466 | 0.182 | 0.039* | 0.077 | 0.000 | 0.046* | 0.084 | 0.759 | 0.388 | 0.708 | 0.397 | 0.042* | 0.381 | |
SKBR3-BAX | Correlation coefficient | − 0.945 | − 0.903 | 0.136 | 0.051 | − 0.800 | − 0.997 | − 0.811 | 0.694 | − 0.977 | − 0.991 | 0.981 | 0.997 | 1.000 | 0.979 | − 0.437 | 0.860 | − 0.376 | − 0.767 | 1.000 | 0.783 |
Significance (2-tailed) | 0.211 | 0.283 | 0.913 | 0.968 | 0.410 | 0.049* | 0.398 | 0.512 | 0.136 | 0.085 | 0.124 | 0.046* | 0.000 | 0.130 | 0.712 | 0.341 | 0.754 | 0.443 | 0.004** | 0.427 | |
SKBR3-BCL2 | Correlation coefficient | − 0.860 | − 0.971 | 0.334 | 0.252 | − 0.905 | − 0.992 | − 0.913 | 0.825 | − 0.914 | − 0.998 | 1.000 | 0.991 | 0.979 | 1.000 | − 0.245 | 0.738 | − 0.556 | − 0.881 | 0.981 | 0.893 |
Significance (2-tailed) | 0.341 | 0.153 | 0.783 | 0.838 | 0.280 | 0.081 | 0.268 | 0.382 | 0.266 | 0.045* | 0.006 | 0.084 | 0.130 | 0.000 | 0.843 | 0.471 | 0.624 | 0.313 | 0.126 | 0.297 | |
SKBR3-CASP3 | Correlation coefficient | 0.706 | 0.007 | 0.832 | 0.876 | − 0.191 | 0.366 | − 0.172 | 0.345 | 0.617 | 0.313 | − 0.255 | − 0.370 | − 0.437 | − 0.245 | 1.000 | − 0.835 | − 0.669 | − 0.242 | − 0.430 | 0.217 |
Significance (2-tailed) | 0.501 | 0.995 | 0.374 | 0.320 | 0.878 | 0.762 | 0.890 | 0.776 | 0.576 | 0.798 | 0.836 | 0.759 | 0.712 | 0.843 | 0.000 | 0.371 | 0.533 | 0.844 | 0.717 | 0.860 | |
T47D-p53 | Correlation coefficient | − 0.979 | − 0.557 | − 0.389 | − 0.467 | − 0.381 | − 0.818 | − 0.398 | 0.228 | − 0.948 | − 0.784 | 0.745 | 0.820 | 0.860 | 0.738 | − 0.835 | 1.000 | 0.150 | − 0.332 | 0.856 | 0.356 |
Significance (2-tailed) | 0.130 | 0.624 | 0.746 | 0.691 | 0.751 | 0.391 | 0.739 | 0.853 | 0.205 | 0.427 | 0.465 | 0.388 | 0.341 | 0.471 | 0.371 | 0.000 | 0.904 | 0.785 | 0.346 | 0.769 | |
T47D-p27 | Correlation coefficient | 0.054 | 0.738 | − 0.969 | − 0.944 | 0.857 | 0.447 | 0.847 | − 0.928 | 0.171 | 0.496 | − 0.548 | − 0.442 | − 0.376 | − 0.556 | − 0.669 | 0.150 | 1.000 | 0.883 | − 0.382 | − 0.871 |
Significance (2-tailed) | 0.966 | 0.472 | 0.159 | 0.213 | 0.345 | 0.705 | 0.357 | 0.243 | 0.890 | 0.669 | 0.631 | 0.708 | 0.754 | 0.624 | 0.533 | 0.904 | 0.000 | 0.311 | 0.750 | 0.327 | |
T47D-BAX | Correlation coefficient | 0.516 | 0.968 | − 0.740 | − 0.680 | 0.999 | 0.814 | 0.997 | − 0.994 | 0.614 | 0.846 | − 0.876 | − 0.812 | − 0.767 | − 0.881 | − 0.242 | − 0.332 | 0.883 | 1.000 | − 0.771 | − 1.000 |
Significance (2-tailed) | 0.655 | 0.161 | 0.470 | 0.524 | 0.034 | 0.394 | 0.046 | 0.069 | 0.579 | 0.358 | 0.320 | 0.397 | 0.443 | 0.313 | 0.844 | 0.785 | 0.311 | 0.000 | 0.439 | 0.016* | |
T47D-BCL2 | Correlation coefficient | − 0.943 | − 0.906 | 0.143 | 0.057 | − 0.804 | − 0.997 | − 0.815 | 0.698 | − 0.976 | − 0.992 | 0.982 | 0.998 | 1.000 | 0.981 | − 0.430 | 0.856 | − 0.382 | − 0.771 | 1.000 | 0.787 |
Significance (2-tailed) | 0.216 | 0.279 | 0.909 | 0.963 | 0.405 | 0.045 | 0.393 | 0.508 | 0.140 | 0.081 | 0.119 | 0.042* | 0.004** | 0.126 | 0.717 | 0.346 | 0.750 | 0.439 | 0.000 | 0.423 | |
T47D-CASP3 | Correlation coefficient | − 0.538 | − 0.974 | 0.723 | 0.661 | − 1.000 | − 0.829 | − 0.999 | 0.991 | − 0.634 | − 0.859 | 0.888 | 0.826 | 0.783 | 0.893 | 0.217 | 0.356 | − 0.871 | − 1.000 | 0.787 | 1.000 |
Significance (2-tailed) | 0.638 | 0.144 | 0.486 | 0.541 | 0.017* | 0.378 | 0.029* | 0.085 | 0.563 | 0.342 | 0.304 | 0.381 | 0.427 | 0.297 | 0.860 | 0.769 | 0.327 | 0.016* | 0.423 | 0.000 |