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Fig. 5 | Cancer Nanotechnology

Fig. 5

From: Nanotechnology approaches to addressing HER2-positive breast cancer

Fig. 5

(Reprinted with permission from near-infrared quantum dots for HER2 localization and imaging of cancer cells (Rizvi et al. 2014). Originally published by Dove Medical Press Limited)

Methodology of bioconjugation of mercaptoundecanoic acid-coated QDs and application for localization of HER2 receptors. Anti-HER2-AB conjugates to the QD surface through an amide linkage. The QD-Anti-HER-AB conjugate then targets and localizes to the HER2 receptors overexpressed on SK-BR-3 cells. Ab, antibody; HER2, human epidermal growth factor receptor 2; QD, quantum dot

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