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Table 1 The top 57 proteins from the chicken liver extract divided into functional activities according to UniProt database, including the name of the gene and the molecular mass of the protein (kDa)

From: Graphene oxide nanofilm and chicken embryo extract decrease the invasiveness of HepG2 liver cancer cells

No. Gene name Protein name Molecular mass (kDa)
Adhesion
 1 TJP2 Tight junction protein ZO-2 130.7
 2 LARP1 La-related protein 1 118.6
 3 CDH1 Cadherin-1 97.8
 4 CD2AP CD2-associated protein 71.2
 5 tr|A0A1D5PRE3|A0A1D5PRE3_CHICK N-myc downstream regulated 39.0
 6 EPCAM Epithelial cell adhesion molecule 34.4
 7 MTDH Metadherin 14.2
 8 BSG Basigin Few isoforms
ECM organisation
 9 LAMA1 Laminin subunit alpha-1 339.1
 10 COL12A1 Collagen alpha-1(XII) chain 333.5
 11 FN1 Fibronectin 273.2
 12 COL5A1 Collagen alpha-1(V) chain 184.2
 13 LAMC1 Laminin subunit gamma-1 176.5
 14 PEPD Xaa-Pro dipeptidase 55.1
 15 VTN Vitronectin 51.7
 16 PRDX4 Peroxiredoxin-4 29.6
Migration and EMT
 17 PTPN23 Tyrosine-protein phosphatase non-receptor type 23 179.0
 18 FAM98A Protein FAM98A 58.6
 19 TWF1 Twinfilin-1 55.2
 20 MGLL Monoglyceride lipase 33.3
 21 TPM1 Tropomyosin alpha-1 chain 32.8
 22 PBLD Phenazine biosynthesis-like domain-containing protein 32.2
 23 ADI1 1,2-Dihydroxy-3-keto-5-methylthiopentene dioxygenase 21.7
Proliferation and cell cycle
 24 GOLGA2 Golgin subfamily A member 2 140.1
 25 MOV10 Putative helicase MOV-10 109.1
 26 ASMTL Probable bifunctional dTTP/UTP protein pyrophosphatase/methyltransferase 70.2
 27 RPA1 Replication protein A 70-kDa DNA-binding subunit 68.0
 28 ARID3A AT-rich interactive domain-containing protein 3A 67.4
 29 RIC8B Guanine nucleotide exchange factor B 60.5
 30 CERS2 Ceramide synthase 2 55.1
 31 KRT18 Keratin, type I cytoskeletal 18 46.9
 32 MRPS27 28S ribosomal protein S27, mitochondrial 46.7
 33 TARDBP DNA-binding protein 43 44.6
 34 CA9 Carbonic anhydrase 9 43.8
 35 DRG1 Developmentally regulated GTP-binding protein 1 40.5
 36 SLC35F6 Solute carrier family 35 member F6 40.2
 37 AIMP2 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 34.5
 38 FBXO6 F-box only protein 6 30.7
 39 HPGD 15-Hydroxyprostaglandin dehydrogenase [NAD(+)] 29.0
 40 PSMD9 26S proteasome non-ATPase regulatory subunit 9 22.7
 41 NIT2 Nitrilase NIT2 22.1
 42 DYNLL1 Dynein light chain 10.3
Apoptosis
 43 HTT Huntingtin 344.0
 44 PARP1 Poly [ADP-ribose] polymerase 113.1
 45 DNMT3A DNA (cytosine-5)-methyltransferase 3A 99.0
 46 ATAD3A ATPase family AAA domain-containing protein 3A 67.2
 47 SGPL1 Sphingosine-1-phosphate lyase 1 61.1
 48 CTSC Dipeptidyl peptidase 1 59.4
 49 FKBP8 Peptidylprolyl isomerase 44.3
 50 AIFM2 Apoptosis-inducing factor 2 40.6
 51 APIP Methylthioribulose-1-phosphate dehydratase 26.8
 52 PDCD10 Programmed cell death protein 10 24.7
 53 ENDOG Endonuclease G, mitochondrial 22.2
 54 FAM162A Protein FAM162A 17.1
 55 HIGD1A HIG1 domain family member 1A, mitochondrial 10.7
 56 DYNLL1 Dynein light chain 10.3
 57 NQO1 NAD(P)H dehydrogenase [quinone] 1 Few isoforms