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Fig. 4 | Cancer Nanotechnology

Fig. 4

From: Curcumin-enriched Gemini surfactant nanoparticles exhibited tumoricidal effects on human 3D spheroid HT-29 cells in vitro

Fig. 4

The Rhodamine 123 efflux assay (a). Flow cytometry analysis revealed the loss of Rhodamine 123 efflux capacity in 3D spheroid HT-29 cells after 48 h of incubation with Gemini-Cur NPs. The cells lost Rhodamine 123 efflux capacity after being treated with Gemini-Cur NPs in a dose-dependent manner. Analysis of cell migration by Transwell inserts assay (b). The migration of 3D spheroid HT-29 cells was decreased upon treatment with 80 and 300 Gemini-Cur NPs after 48 h, indicating the inhibition of cell migration in a 3D culture system exposed to Gemini-Cur NPs

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Cancer Nanotechnology

ISSN: 1868-6966

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