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Fig. 5 | Cancer Nanotechnology

Fig. 5

From: Methylene blue associated with maghemite nanoparticles has antitumor activity in breast and ovarian carcinoma cell lines

Fig. 5

Cell death profile after 48 h of MAGCIT–MB treatment (0.78 µg mL−1 of MB). a Dot plots representing the distribution of apoptotic and necrotic cells after dual staining with Annexin-V-FITC (horizontal axis) and propidium iodide (vertical axil). Results demonstrate live cells (lower left quadrant), early apoptosis (upper left quadrant), late apoptosis (upper right quadrant) and necrosis (lower right quadrant). b Percentage of cells presented. Groups: untreated cells (NT) and MAGCIT–MB. Data are presented as mean ± SD from three experiments. **p < 0.01, ***p < 0.001 and ****p < 0.0001. *Treatment compared to NT control

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