Fig. 9
From: Recent progress of graphene oxide-based multifunctional nanomaterials for cancer treatment
(Reproduced with permission (Chen et al. 2016). Copyright 2016, Nanoscale Research Letters)
Illustration of rNGO–PEG/ICG for in vivo photoacoustic/fluorescence dual-modality tumor imaging. a The synthesis route of rNGO–PEG/ICG. b In vivo fluorescence imaging. (i). Fluorescence signal distribution within the tumor-bearing mouse body as a function of time after tail vein injection of ICG and rNGO–PEG/ICG. White dash line encircles the tumor region. (ii, iii). The ex vivo fluorescence signal of the excised major organs (tumor, heart, liver, spleen, lung, and kidney) and tumor slices of mice at 48 h post-injection