Skip to main content
Fig. 3 | Cancer Nanotechnology

Fig. 3

From: Emodin-loaded polymer-lipid hybrid nanoparticles enhance the sensitivity of breast cancer to doxorubicin by inhibiting epithelial–mesenchymal transition

Fig. 3

Effect of Galunisertib combined with DOX on apoptosis and expression of drug resistance protein. A, B The apoptotic rate of MCF-7/ADR cells treated with different groups (DOX, Galunisertib, DOX + Galunisertib) was measured by flow cytometry. C, D The expression of Bax and Bcl-2 in MCF-7/ADR cells treated with DOX, Galunisertib, DOX + Galunisertib. Relative levels of the proteins were quantified by densitometric analysis. E, F The expression of P-gp and MRP1 in MCF-7/ADR cells treated with different groups (DOX, Galunisertib, DOX + Galunisertib). N = 3, **p < 0.01, ***p < 0.001 compared with DOX group

Back to article page