From: Antitumor efficiency of the natural alkaloid berberine complexed with C60 fullerene in Lewis lung carcinoma in vitro and in vivo
IC50, µM
24 h
48 h
72 h
Ber
43 ± 4
25 ± 2
17 ± 2
1:2 C60–Ber
39 ± 4
22 ± 2
14 ± 1*
1:1 C60–Ber
26 ± 3*
13 ± 2*
7.5 ± 2.3*
2:1 C60–Ber
6.4 ± 1.7*
4.0 ± 1.6*
0.8 ± 0.3*