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Table 2 Pharmacokinetics parameters of GNP theranostic nanomedicines after PO administration

From: A novel formulation of theranostic nanomedicine for targeting drug delivery to gastrointestinal tract cancer

Sr#

*Pharmacokinetics

Parameters

Mean values

(n = 3)

1

C°(µg/ml)

176

2

Cmax (µg/ml)

0.338 ± 0.006

3

tmax(h)

48

4

AUC (h.mg/L)

15.48 ± 2.1

5

Vd (L/kg)

0.0284

6

p-value

 < 0.001

  1. C°, initial plasma drug concentration at the time of injection; Cmax, maximum plasma concentration at observed points; tmax, time at which the maximum concentration was noted; t1/2, plasma half-life; AUC, area under the plasma concentration time profile curve; K, elimination constant; CL, clearance rate; Vd, distribution volume
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Cancer Nanotechnology

ISSN: 1868-6966

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