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Table 5 Effect of nanoLPG on hematological parameters

From: Promising self-emulsifying drug delivery system loaded with lycopene from red guava (Psidium guajava L.): in vivo toxicity, biodistribution and cytotoxicity on DU-145 prostate cancer cells

Parameter

Control

NanoLPG

Hematocrit (%)

48.60 ± 0.51

46.13 ± 0.85

Erythrocytes (× 106 cells/µL)

09.95 ± 0.13

09.39 ± 0.20

Hemoglobin (g/dL)

17.72 ± 0.55

18.14 ± 1.29

MCV (fL)

48.82 ± 0.79

49.23 ± 1.11

MCHC (%)

36.44 ± 1.08

39.36 ± 2.89

Leukocytes (cells/µL)

5,750 ± 1096

4,275 ± 575

Monocytes (%)

2.20 ± 0.37

2.37 ± 0.59

Lymphocytes (%)

79.80 ± 2.15

76.88 ± 1.96

Eosinophils (%)

0.60 ± 0.24

0.25 ± 0.16

Basophils (%)

0.00 ± 0.00

0.00 ± 0.00

Band cell (%)

0.00 ± 0.00

0.00 ± 0.00

Segmented neutrophils (%)

17.40 ± 2.31

20.50 ± 2.03

Platelets (cells/µL)

800,000 ± 107,165

897,250 ± 66,576

Total plasmatic proteins (g/dL)

6.56 ± 0.29

6.85 ± 0.88

  1. Data were expressed as mean ± SEM. MCV: mean corpuscular volume. MCHC: mean corpuscular hemoglobin concentration. N = 5–9 animals per group