Fig. 6

Hemolytic activity and viability of monocytic THP-1 cells after addition of folate-conjugated polymers (A and D), folate-conjugated polymers with 5-FU (B and E), and 5-FU (C and F). Statistical significance for the folate-conjugated polymers without or with 5-FU or 5-FU vs control was marked with (*); comparison of 5-FU concentration at free vs encapsulated form 5-FU 5 µg/mL vs 0.1 mg/mL + 5-FU 5 µg/mL marked with (#) and 5-FU 25 µg/mL vs 0.5 mg/mL + 5-FU 25 µg/mL marked with (^), p ≤ 0.05. The data presented constitute average results from three measurements ± SD