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Fig. 5 | Cancer Nanotechnology

Fig. 5

From: Baicalin-loaded folic acid-modified albumin nanoparticles (FA-BSANPs/BA) induce autophagy in MCF-7 cells via ROS-mediated p38 MAPK and Akt/mTOR pathway

Fig. 5

FA-BSANPs/BA regulated p38 MAPK and Akt/mTOR signaling pathways in MCF-7 cells. A Expression of p38 MAPK and Akt/mTOR pathway proteins after treatment with FA-BSANPs/BA. B Expression of p-p38 MAPK, apoptosis- and autophagy-related proteins after treatment with FA-BSANPs/BA or/and SB203580. C Expression of Ak/mTOR pathway proteins, apoptosis- and autophagy-related proteins after treatment with FA-BSANPs/BA, MK2206 or/and rapamycin. D, E Evaluation of cell viability. Results are shown as mean ± SD (n = 3), *p < 0.05, **p < 0.01, ***p < 0.001

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