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Table 2 Kinetic equations of BA release from FA-BSANPs/BA

From: Baicalin-loaded folic acid-modified albumin nanoparticles (FA-BSANPs/BA) induce autophagy in MCF-7 cells via ROS-mediated p38 MAPK and Akt/mTOR pathway

pH of release medium Fitting curve Regression equation R2
7.4# First-order equation Mt = 89.14(1−e−0.12t) 0.98184
6.5 Zero-order equation Mt = 1.55t + 26.01 0.79138
First-order equation Mt = 84.78(1−e−0.11t) 0.97805
Higuchi equation Mt = 13.29t0.5 + 4.79 0.93049
5.5 Zero-order equation Mt = 0.89t + 19.99 0.68458
First-order equation Mt = 51.59(1−e−0.15t) 0.93788
Higuchi equation Mt = 7.74t0.5 + 7.43 0.83477
  1. Mt: cumulative release rate of drug (%)
  2. t time (h)
  3. #Data of pH7.4 were quoted from reference (Meng et al. 2021), and we have obtained permission from the copyright holder to reproduce it