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Fig. 5 | Cancer Nanotechnology

Fig. 5

From: Synergistic co-administration of docetaxel and curcumin to chemoresistant cancer cells using PEGylated and RIPL peptide-conjugated nanostructured lipid carriers

Fig. 5

Cell apoptosis of MCF7 and MCF7/ADR cells after treatment with docetaxel (DTX)- or curcumin (CUR)-loaded formulations at 100 ng/mL DTX-equivalent concentration (DTX:CUR = 1:3, w/w) for 24 h. A The scatter plots and B quantitative analysis of cell apoptotic death (%), calculated as the sum of the early apoptosis rate and the late apoptosis rate. Significant differences at p < 0.05: * versus DTX-Sol; # versus DTX-pNLC; @ versus DTX-Sol + CUR-Sol. Data represent mean ± SD (n = 3). Top left (Q1, Annexin–/PI+), necrotic cells; top right (Q2, Annexin+/PI+), late apoptotic cells; bottom left (Q3, Annexin–/PI–), live cells; bottom right (Q4, Annexin+/PI–), early apoptotic cells

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Cancer Nanotechnology

ISSN: 1868-6966

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