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Fig. 4 | Cancer Nanotechnology

Fig. 4

From: Multifunctional nanocomposites DDMplusAF inhibit the proliferation and enhance the radiotherapy of breast cancer cells via modulating tumor-promoting factors and metabolic reprogramming

Fig. 4

Cell survival and radiosensitizing capability of DDMPlusAF combined with different γ-radiation doses in BCCs generated using M-MTT assay at 24, 48, and 72 h. a Schematic diagram illustrates the scheme of experimental procedures for the M-MTT assay, b and c surviving fractions (SF) of MCF-7 and MDA-MB-231 cells, respectively, treated with DDMPlusAF and/or γ-radiation at 3 and 6 Gy. d and e Dose-modifying factor (DMF) curves of MCF-7 and MDA-MB-231cells, respectively. Data are represented as mean ± SEM, where the control cells are set at 85% confluence (n = 3). ap < 0.001 vs. control; bp < 0.001 vs. 3 Gy; cp < 0.001 vs. 6 Gy groups; dp < 0.001 vs. DDMPlusAF group and ep < 0.05 vs. DDMPlusAF + 3 Gy group

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Cancer Nanotechnology

ISSN: 1868-6966

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