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Table 3 Effect of lyophilization and storage temperature on the stability of CPMSD (n = 3)

From: Nanomicelles co-loaded with doxorubicin and salvianolic acid A for breast cancer chemotherapy

Parameters

Lyophilization

Storagea

Before

After

4 °C

1 week

25 °C

1 week

4 °C

1 month

25 °C

1 month

Particle size (nm)

21.6 ± 1.5

20.2 ± 2.6

21.9 ± 1.7

21.2 ± 1.0

22.6 ± 2.1

23.8 ± 2.3

DLC (%)

16.1 ± 0.6

16.2 ± 0.8

16.2 ± 1.2

16.8 ± 1.2

15.9 ± 1.9

16.4 ± 0.4

EE (%)

99.6 ± 3.4

97.7 ± 2.8

96.8 ± 4.0

95.2 ± 3.1

96.9 ± 3.9

96.2 ± 2.1

  1. aThe data are collected from the lyophilized powders of CPMSD