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Table 4 Model fitting for in vitro drug release from nanomicelles of CPMSD micelles

From: Nanomicelles co-loaded with doxorubicin and salvianolic acid A for breast cancer chemotherapy

Model

DOXa

SAAa

Zero-order equation

Y = 0.78t + 71.07 (0.2103)

Y = 0.86t + 21.50 (0.7811)

First-order equation

Y = 87.66 [1 − exp(− 1.26t)] (0.9819)

Y = 65.18 [1 − exp(− 0.10t)] (0.9765)

Higuchi equation

Y = 6.36t1/2 + 61.67 (0.4924)

Y = 8.55t1/2 + 7.05 (0.9402)

  1. aThe data in parenthesis are the determination coefficient for model fitting