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Table 2 Analysis of the combined effect of Fe3O4@Cus–PEG nanoparticles and ionizing radiation. The values were represented by the mean ± SD of three independent experiments

From: Improve the cytotoxic effects of megavoltage radiation treatment by Fe3O4@Cus–PEG nanoparticles as a novel radiosensitizer in colorectal cancer cells

Dose

Based on the MTT data

Based on the colony data

[NP + IR]

[NP] × [IR]/100

P value

[NP + IR]

[NP] × [IR]/100

P value

2 Gy

62 ± 1

81.4 ± 1.1

0.0001

56 ± 2.6

80.2 ± 5.3

0.0001

4 Gy

41.1 ± 1.3

65.2 ± 0.35

0.0001

31.6 ± 2.1

56 ± 0.47

0.0001

6 Gy

25.1 ± 1.4

42.9 ± 3.7

0.0001

15 ± 2

32.2 ± 4.7

0.0001

  1. [NP], [IR], and [NP + IR] represent the percentage of cell viability or survival fraction after treatments with Fe3O4@Cus–PEG NPs, ionizing radiation, and combination of nanoparticles with ionizing radiation, respectively
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Cancer Nanotechnology

ISSN: 1868-6966

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