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Fig. 4 | Cancer Nanotechnology

Fig. 4

From: A novel pH- and glutathione-responsive drug delivery system based on in situ growth of MOF199 on mesoporous organic silica nanoparticles targeting the hepatocellular carcinoma niche

Fig. 4

Apoptosis and proliferation process. A AO-EB fluorescent staining assay; scale bar is 200 µm. B Cell proliferation study by EdU test; scale bar is 200 µm. C-F Western blot analysis of Bcl-2, BAX, and Cl-Caspase 3 expression, * represents p < 0.05 and ** represents p < 0.01. PBS (a), MONs@MOF-199 (b), free DOX/SOR (c), D/S@MM (d), and D/S@SPMM (e)

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