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Fig. 4 | Cancer Nanotechnology

Fig. 4

From: Low-dose pleiotropic radiosensitive nanoformulations for three-pronged radiochemotherapy of hypoxic brain glioblastoma under BOLD/DWI monitoring

Fig. 4

BBB transport and brain targeting in vitro and in vivo. A Penetration percentage of SLC-SN@AQ NPs and SLC-AN/SN@AQ NPs through in vitro BBB model. Free ANG pretreatment was used as blocking. B Ln content in the plasma and brain of the glioma-bearing mice determined by ICP-OES after intravenous injection of NPs with and without ANG modification. C Fluorescence images of the living glioma-bearing mice and their ex vivo tissues at 24 h post-injection of Cy5.5-labeled NPs with and without ANG modification. D Quantitative analysis of fluorescence intensity in brains in (C)

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