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Fig. 1 | Cancer Nanotechnology

Fig. 1

From: Development of glycan-targeted nanoparticles as a novel therapeutic opportunity for gastric cancer treatment

Fig. 1

Development of sTn-targeted nanoparticles loaded with dsRNA targeting ST6GalNAc-I or galectin-3. A Schematic representation of poly-lactic acid nanoparticles (PLA-NP) development. PLA-NP were prepared by the double emulsion solvent evaporation method with poly-lactic acid polymer (PLA), dsRNA (double strand RNA against ST6GalNAc-I, galectin-3 or random), didodecyldimethylammonium bromide (DDAB) and anti-sTn antibody. B Table shows the mean size and polydispersity index of sTn-targeted and non-targeted NPs loaded with dsRNA-galectin-3, dsRNA-ST6GalNAc-I or dsRNA-random. C Representative images of sTn-targeted and non-targeted NPs by TEM

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