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Fig. 5 | Cancer Nanotechnology

Fig. 5

From: Lipo-MGN nanoparticle hypoxia attenuation-mediated single-dose radiotherapy- and pH/ROS-responsive T1 contrast magnetic resonance imaging in hepatocellular carcinoma

Fig. 5

In vitro MRI study of Lipo-MGN at different H2O2 concentrations and pH values. A T1-weighted MR contrast images of Lipo-MGNs from 0 to 2 mM concentrations at pH 6.8–7.4 and at 0.1 mM and 1 mM H2O2 concentrations. B Graph plotting the contrast signal intensity of Lipo-MGNs from 0 to 2 mM concentrations at pH 6.8–7.4 and at 0.1 mM and 1 mM H2O2 concentrations. The data are presented as the mean ± standard error of the mean with number of samples (n) = 3. The mean signal intensity significant differences between three groups at different Mn concentration as analyzed by repeated measure ANOVA test and in the post hoc analysis by Tukeys test (pH 7.4 + 0.1 mM H2O2 vs. pH 6.8 + 1 mM H2O2: *P < 0.05)

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