Skip to main content
Fig. 2 | Cancer Nanotechnology

Fig. 2

From: Targeting and sensitizing MDR cancer by an MMP2 and pH dual-responsive ZnO-based nanomedicine

Fig. 2

A Cellular uptake of the DOX-loaded ZnO-based NPs after 1 h incubation with the MDR cancer cells (NCI/ADR-RES), determined by flow cytometry. MFI, mean fluorescence intensity. B Confocal microscopic images of cellular internalization of the ZnO/DPPG/PEG-PE/DOX and ZnO/DPPG/PEG-pp-PE/DOX with or without the MMP2 pretreatment after 1 h incubation with the NCI/ADR-RES cells. Cell nuclei were stained by Hoechst (blue). The scale bar is 100 μm. Data were expressed as the mean ± SD, **p < 0.01; ***p < 0.001

Back to article page