Fig. 4From: Targeting and sensitizing MDR cancer by an MMP2 and pH dual-responsive ZnO-based nanomedicineA Cytotoxicity of the DOX-loaded ZnO-based NPs with/without the MMP2 pretreatment after 24 h incubation with the MDR cancer cells (NCI/ADR-RES). B Cell viability of the NCI/ADR-RES spheroids after 72 h treatments, measured by the CellTiter-Blue® Cell Viability Assay. Data were expressed as the mean ± SD, **p < 0.01; ***p < 0.001Back to article page