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  1. Berberine (Ber) is a herbal alkaloid with pharmacological activity in general and a high anticancer potency in particular. However, due to its low bioavailability, the difficulty in reaching a target and choos...

    Authors: Anna Grebinyk, Svitlana Prylutska, Sergii Grebinyk, Maxim Evstigneev, Iryna Krysiuk, Tetiana Skaterna, Iryna Horak, Yanfang Sun, Liudmyla Drobot, Olga Matyshevska, Yuriy Prylutskyy, Uwe Ritter and Marcus Frohme
    Citation: Cancer Nanotechnology 2021 12:24
  2. The role of epithelial–mesenchymal transition (EMT) involved in breast cancer metastasis and chemoresistance has been increasingly recognized. However, it is necessary to search for more effective strategies t...

    Authors: Tengteng Zou, Meng Lan, Fengjie Liu, Lihong Li, Tiange Cai, Huaqin Tian and Yu Cai
    Citation: Cancer Nanotechnology 2021 12:22
  3. Immune evasion is an important hallmark of cancer progression and tumourigenesis. Among the cancer types, cervical cancer has very high global prevalence, severely affecting female reproductive health. Its pre...

    Authors: Rituparna Chakraborty, Ujjal Bose, Goutam Pawaskar, Satish Rao Bola Sadashiva and Ritu Raval
    Citation: Cancer Nanotechnology 2021 12:21
  4. Cancer is one of the most common incident in the world, with malignant tumors having a death rate of up to 19%. A new method of treating cancer cells effectively with minimal cytotoxicity is needed. In the fie...

    Authors: Naseer Ullah Khan, Jing Lin, Muhammad Rizwan Younas, Xukun Liu and Liming Shen
    Citation: Cancer Nanotechnology 2021 12:20
  5. Combination chemo-photothermal therapy appears to be one of the next generations of cancer treatment. In this study hollow gold nanostars (HGNSs) and gold nanocages (GNCs) were synthesized and stabilized with ...

    Authors: Asrin Pakravan, Mehdi Azizi, Fariborz Rahimi, Farhad Bani, Farideh Mahmoudzadeh, Roya Salehi and Mehrdad Mahkam
    Citation: Cancer Nanotechnology 2021 12:19
  6. In the last decade, graphene oxide-based nanomaterials, such as graphene oxide (GO) and reduced graphene oxide (rGO), have attracted more and more attention in the field of biomedicine. Due to the versatile su...

    Authors: Lijun Liu, Qingming Ma, Jie Cao, Yang Gao, Shangcong Han, Yan Liang, Tingting Zhang, Yang Song and Yong Sun
    Citation: Cancer Nanotechnology 2021 12:18
  7. Glioblastoma multiforme (GBM) is one of the most daunting issues to modern therapeutics, with a higher mortality rate post-diagnosis. Temozolomide (TMZ) is the only available treatment; however, the frequent r...

    Authors: Fawad Ur Rehman, Mohd Ahmar Rauf, Sajjad Ullah, Sana Shaikh, Aqsa Qambrani, Pir Muhammad and Sumaira Hanif
    Citation: Cancer Nanotechnology 2021 12:17
  8. In our earlier work, we identified microRNA-10b (miR10b) as a master regulator of the viability of metastatic tumor cells. This knowledge allowed us to design a miR10b-targeted therapeutic consisting of an ant...

    Authors: Mariane Le Fur, Alana Ross, Pamela Pantazopoulos, Nicholas Rotile, Iris Zhou, Peter Caravan, Zdravka Medarova and Byunghee Yoo
    Citation: Cancer Nanotechnology 2021 12:16
  9. Melittin, a peptide component of honey bee venom, is an appealing candidate for cancer therapy. In the current study, melittin, melittin-loaded niosome, and empty niosome had been optimized and the anticancer ...

    Authors: Farnaz Dabbagh Moghaddam, Iman Akbarzadeh, Ehsan Marzbankia, Mahsa Farid, Leila khaledi, Amir Hossein Reihani, Mehrnoosh Javidfar and Pejman Mortazavi
    Citation: Cancer Nanotechnology 2021 12:14
  10. Brain metastases from non-small cell lung cancer (NSCLC) remain one of the most challenging malignancies. Afatinib (Afa) is an orally administered irreversible ErbB family blocker approved for epidermal growth...

    Authors: Yu-Li Lo, Hua-Ching Lin, Shu-Ting Hong, Chih-Hsien Chang, Chen-Shen Wang and Anya Maan-Yuh Lin
    Citation: Cancer Nanotechnology 2021 12:13
  11. Neuroblastoma is the most common extracranial solid malignancy in childhood which, despite the current progress in radiotherapy and chemotherapy protocols, still has a high mortality rate in high risk tumors. ...

    Authors: William Liu, Salida Mirzoeva, Ye Yuan, Junjing Deng, Si Chen, Barry Lai, Stefan Vogt, Karna Shah, Rahul Shroff, Reiner Bleher, Qiaoling Jin, Nghia Vo, Remon Bazak, Carissa Ritner, Stanley Gutionov, Sumita Raha…
    Citation: Cancer Nanotechnology 2021 12:12
  12. Cancer constitutes group of diseases responsible for the second largest cause of global death, and it is currently considered one of the main public health concerns nowadays. Early diagnosis associated with th...

    Authors: Ana Luísa G. Silva, Natália V. Carvalho, Leonardo G. Paterno, Ludmilla D. Moura, Cleber L. Filomeno, Eneida de Paula and Sônia N. Báo
    Citation: Cancer Nanotechnology 2021 12:11
  13. In this label-free bioassay, an electrochemiluminescence (ECL) immunosensor was developed for the quantification of breast cancer using HER-2 protein as a metastatic biomarker.

    Authors: Hassan Nasrollahpour, Ibrahim Isildak, Mohammad-Reza Rashidi, Esmat Alsadat Hashemi, Abdolhosein Naseri and Balal Khalilzadeh
    Citation: Cancer Nanotechnology 2021 12:10
  14. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Monika Ruzycka-Ayoush, Patrycja Kowalik, Agata Kowalczyk, Piotr Bujak, Anna M. Nowicka, Maria Wojewodzka, Marcin Kruszewski and Ireneusz P. Grudzinski
    Citation: Cancer Nanotechnology 2021 12:9

    The original article was published in Cancer Nanotechnology 2021 12:8

  15. Lung cancer is one of the most frequently diagnosed cancers all over the world and is also one of the leading causes of cancer-related mortality. The main treatment option for small cell lung cancer, conventio...

    Authors: Monika Ruzycka-Ayoush, Patrycja Kowalik, Agata Kowalczyk, Piotr Bujak, Anna M. Nowicka, Maria Wojewodzka, Marcin Kruszewski and Ireneusz P. Grudzinski
    Citation: Cancer Nanotechnology 2021 12:8

    The Correction to this article has been published in Cancer Nanotechnology 2021 12:9

  16. Magnetic fluid hyperthermia (MFH) is a successful nanotechnology application in recent decade where a biocompatible magnetic fluid is used to kill cancer cells in a controlled heating using AC magnetic field. ...

    Authors: Anand Bhardwaj, Neeraj Jain and Kinnari Parekh
    Citation: Cancer Nanotechnology 2021 12:7
  17. The skin is both a target and a potential conduit for the delivery of drugs, but its cornified cell layer resists penetration by most molecules. This study investigated the potential of superparamagnetic iron ...

    Authors: Vanisri Raviraj, Binh T. T. Pham, Byung J. Kim, Nguyen T. H. Pham, Lai F. Kok, Nicole Painter, Naomi C. Delic, Stephen K. Jones, Brian S. Hawkett and J. Guy Lyons
    Citation: Cancer Nanotechnology 2021 12:6
  18. Despite advances in glioblastoma (GBM) treatments, current approaches have failed to improve the overall survival of patients. The oncogene BMI-1, a core member of the polycomb group proteins, is a potential n...

    Authors: Elham Poonaki, Fatemeh Ariakia, Mohammad Jalili-Nik, Mehdi Shafiee Ardestani, Gholamhossein Tondro, Fariborz Samini, Sepideh Ghasemi, Sajad Sahab-Negah and Ali Gorji
    Citation: Cancer Nanotechnology 2021 12:5
  19. In this study, we report on the synthesis, imaging, and radiosensitizing properties of ultrasmall β-NaGdF4:Yb50% nanoparticles as a multifunctional theranostic platform. The synthesized nanoparticles act as poten...

    Authors: Jossana A. Damasco, Tymish Y. Ohulchanskyy, Supriya Mahajan, Guanying Chen, Ajay Singh, Hilliard L. Kutscher, Haoyuan Huang, Steven G. Turowski, Joseph A. Spernyak, Anurag K. Singh, Jonathan F. Lovell, Mukund Seshadri and Paras N. Prasad
    Citation: Cancer Nanotechnology 2021 12:4
  20. Here, we examined the tumoricidal effect of Gemini surfactant nanoparticles enriched with curcumin on 3D spheroid HT-29 cells. The delivery of curcumin and other phytocompounds to the tumor niche is an importa...

    Authors: Zohre Zibaei, Esmaeil Babaei, Arezoo Rezaie Nezhad Zamani, Reza Rahbarghazi and Hewa Jalal Azeez
    Citation: Cancer Nanotechnology 2021 12:3
  21. The extracellular matrix (ECM) is a mosaic of various structural and functional proteins that cooperate with the cell, regulate adhesion, and consequently manage its further fate. Liver destruction is accompan...

    Authors: Malwina Sosnowska, Marta Kutwin, Barbara Strojny, Piotr Koczoń, Jarosław Szczepaniak, Jaśmina Bałaban, Karolina Daniluk, Sławomir Jaworski, André Chwalibog, Wiesław Bielawski and Ewa Sawosz
    Citation: Cancer Nanotechnology 2021 12:2
  22. Ovarian cancer is one of the deadliest gynecological malignancies. While the overall survival of ovarian cancer patients has slightly improved in recent years in the developed world, it remains clinically chal...

    Authors: Md. Nazir Hossen, Chandra Kumar Elechalawar, Virginie Sjoelund, Kathleen Moore, Robert Mannel, Resham Bhattacharya and Priyabrata Mukherjee
    Citation: Cancer Nanotechnology 2021 12:1
  23. The present study aims to develop a nanoparticle encapsulating doxorubicin (DOX) and programmed death-ligand 1 (PD-L1) siRNA and evaluate its anti-tumor effects on hepatoma carcinoma (HCC).

    Authors: Hanzhang Zhu, Weijiang Zhou, Yafeng Wan, Ke Ge, Jun Lu and Changku Jia
    Citation: Cancer Nanotechnology 2020 11:15
  24. Amphiphilic block copolymers used as nanomicelle drug carriers can effectively overcome poor drug solubility and specificity issues. Hence, these platforms have a broad applicability in cancer treatment. In th...

    Authors: S. Pisano, X. Wang, J. Garcia-Parra, A. Gazze, K. Edwards, V. Feltracco, Y. Hu, L. He, D. Gonzalez, L. W. Francis, R. S. Conlan and C. Li
    Citation: Cancer Nanotechnology 2020 11:14
  25. Breast cancer is therapeutically very challenging to treat as it has the main four known genetic alterations, which result in the existence of several phenotypes leading to the difference in the mode of therap...

    Authors: Sara Al Tamimi, Sarmadia Ashraf, Tahir Abdulrehman, Aijaz Parray, Said A. Mansour, Yousef Haik and Shahnaz Qadri
    Citation: Cancer Nanotechnology 2020 11:13
  26. Breast cancer is a major cause of cancer-associated deaths in the United States. It was estimated that 12% of women in the U.S. will develop invasive breast cancer in their lifetime. The human epidermal growth...

    Authors: Bryan E. White, Molly K. White, Het Adhvaryu, Issam Makhoul, Zeid A. Nima, Alexandru S. Biris and Nawab Ali
    Citation: Cancer Nanotechnology 2020 11:12
  27. Breast cancer (BC), as the most widely recognized disease in women worldwide, represents about 30% of all cancers impacting women. This study was aimed to synthesize Cu2O nanoparticles from the cystoseira myrica ...

    Authors: Parisa Taherzadeh-Soureshjani and Mohammad Chehelgerdi
    Citation: Cancer Nanotechnology 2020 11:11
  28. Cockle shell-derived aragonite calcium carbonate nanoparticles (CACNP) have demonstrated prospect as nano-sized drug carriers for targeting cancer cells. CACNP is biocompatible, biodegradable and its biomateri...

    Authors: Kehinde Muibat Ibiyeye, Sherifat Banke Idris and Abu Bakar Zakaria Zuki
    Citation: Cancer Nanotechnology 2020 11:10
  29. The AGuIX® (NH TherAguix) nanoparticle has been developed to enhance radiotherapy treatment and provide strong MR contrast. These two properties have previously been investigated separately and progressed to clin...

    Authors: H. L. Byrne, G. Le Duc, F. Lux, O. Tillement, N. M. Holmes, A. James, U. Jelen, B. Dong, G. Liney, T. L. Roberts and Z. Kuncic
    Citation: Cancer Nanotechnology 2020 11:9
  30. Successful integration of nanotechnology into the current paradigm of cancer therapy requires proper understanding of the interface between nanoparticles (NPs) and cancer cells, as well as other key components...

    Authors: Kyle Bromma, Aaron Bannister, Antonia Kowalewski, Leah Cicon and Devika B. Chithrani
    Citation: Cancer Nanotechnology 2020 11:8
  31. Doxorubicin-loaded hollow gold nanospheres (Dox@HAuNS) are a promising technology for simultaneous trans-arterial tumor-targeted chemotherapy delivery and thermal ablation. We evaluated the efficacy of intra-a...

    Authors: Rahul A. Sheth, Xiaoxia Wen, Junjie Li, Marites P. Melancon, Xin Ji, Y. Andrew Wang, Cheng-Hui Hsiao, Diana S.-L. Chow, Elizabeth M. Whitley, Chun Li and Sanjay Gupta
    Citation: Cancer Nanotechnology 2020 11:6
  32. The aim of this study was to compare contrast enhancement of Magnevist® (gadopentate dimeglumine (Mag)) to that of PEGylated Magnevist®-loaded liposomal nanoparticles (Mag-Lnps) in pancreatic cancer patient-deriv...

    Authors: Kevin Affram, Taylor Smith, Shannon Helsper, Jens T. Rosenberg, Bo Han, Jose Trevino and Edward Agyare
    Citation: Cancer Nanotechnology 2020 11:5
  33. Nanotechnology is a frequent treatment for cancer. Nanomaterials are the vehicles which deliver drugs in smaller but equally effective quantities. The aim of this investigation is to synthesize gold nanopartic...

    Authors: M. A. González-López, E. M. Gutiérrez-Cárdenas, C. Sánchez-Cruz, J. F. Hernández-Paz, I. Pérez, J. J. Olivares-Trejo and O. Hernández-González
    Citation: Cancer Nanotechnology 2020 11:4
  34. We previously described the properties of a targeted drug delivery system (DDS) in a cell-free system. Here, in this comparative cell-based study (normal and tumor cells), we provide a quantitative analysis of...

    Authors: Marzenna Wiranowska, Rupin Singh, Rana Falahat, Eva Williams, Joseph O. Johnson and Norma Alcantar
    Citation: Cancer Nanotechnology 2020 11:3
  35. The first-line chemotherapy drug that is used to treat pancreatic ductal adenocarcinoma is gemcitabine. Unfortunately, its effectiveness is hampered by its chemo-resistance, low vascularization and drug biodis...

    Authors: Paweł Nalepa, Robert Gawecki, Grzegorz Szewczyk, Katarzyna Balin, Mateusz Dulski, Mieczysław Sajewicz, Anna Mrozek-Wilczkiewicz, Robert Musioł, Jaroslaw Polanski and Maciej Serda
    Citation: Cancer Nanotechnology 2020 11:2
  36. Fluorescent silica nanoparticles have been extensively utilised in a broad range of biological applications and are facilitated by their predictable, well-understood, flexible chemistry and apparent biocompati...

    Authors: Vladimir Gubala, Giorgia Giovannini, Filip Kunc, Marco P. Monopoli and Colin J. Moore
    Citation: Cancer Nanotechnology 2020 11:1
  37. In recent years, disease treatment has evolved strategies that require increase in pharmaceutical agent’s efficacy and selectivity while decreasing their toxicity in normal tissues. These requirements have led...

    Authors: Esteban Beltrán-Gracia, Adolfo López-Camacho, Inocencio Higuera-Ciapara, Jesús B Velázquez-Fernández and Alba A Vallejo-Cardona
    Citation: Cancer Nanotechnology 2019 10:11
  38. A wide range of nanoparticles (NPs), composed of different elements and their compounds, are being developed by several groups as possible radiosensitisers, with some already in clinical trials. However, no sy...

    Authors: Alexandra Guerreiro, Nicholas Chatterton, Eleanor M. Crabb and Jon P. Golding
    Citation: Cancer Nanotechnology 2019 10:10
  39. Heat generated from plasmonic nanoparticles can be utilized in plasmonic photothermal therapy. A combination of near-infrared laser and plasmonic nanoparticles is compelling for the treatment of brain cancer, ...

    Authors: Yue He, Kristoffer Laugesen, Dana Kamp, Salik A. Sultan, Lene B. Oddershede and Liselotte Jauffred
    Citation: Cancer Nanotechnology 2019 10:8
  40. Nanocarriers have the potential to improve the therapeutic index of currently available drugs by increasing drug efficacy, lowering drug toxicity and achieving steady-state therapeutic levels of drugs over an ...

    Authors: Natalia Lemos Chaves, Danilo Aquino Amorim, Cláudio Afonso Pinho Lopes, Irina Estrela-Lopis, Julia Böttner, Aparecido Ribeiro de Souza and Sônia Nair Báo
    Citation: Cancer Nanotechnology 2019 10:7
  41. Ion-beam cancer therapy, an alternative to a common radiation therapy with X-rays, has been used clinically around the world since 1990s; the number of proton therapy centers as well as facilities using heavie...

    Authors: Eugene Surdutovich and Andrey V. Solov’yov
    Citation: Cancer Nanotechnology 2019 10:6
  42. Relative biological effectiveness (RBE) is a key quantity for the description of radiobiological effects induced by charged-particle irradiation in the context of ion-beam cancer therapy. Since RBE is a comple...

    Authors: Alexey Verkhovtsev, Eugene Surdutovich and Andrey V. Solov’yov
    Citation: Cancer Nanotechnology 2019 10:4
  43. This article reviews radiation chemistry processes induced by high-linear energy transfer (LET) radiation. The first part gives a short historical introduction and defines the essential concepts of radiation c...

    Authors: Gérard Baldacchino, Emilie Brun, Ibtihel Denden, Sarah Bouhadoun, Raphael Roux, Hicham Khodja and Cécile Sicard-Roselli
    Citation: Cancer Nanotechnology 2019 10:3
  44. Poly(lactic-co-glycolic acid) (PLGA) is a biodegradable and biocompatible polymer which is widely used as a matrix to incorporate therapeutic agents. The anticancer activity of targeted folate-modified docetaxel-...

    Authors: Yuri I. Poltavets, Alexander S. Zhirnik, Vasilisa V. Zavarzina, Yuliya P. Semochkina, Valentina G. Shuvatova, Anna A. Krasheninnikova, Sergey V. Aleshin, Danil O. Dronov, Eugeny A. Vorontsov, Vadim Yu. Balabanyan and Galina A. Posypanova
    Citation: Cancer Nanotechnology 2019 10:2
  45. Radiotherapy is commonly used for treating cancer. Novel sensitizers, such as gold nanoparticles (GNPs), are being used to enhance the local radiation dose. It is not known how the uptake and radiation dose en...

    Authors: Kyle Bromma, Kristy Rieck, Jayesh Kulkarni, Connor O’Sullivan, Wonmo Sung, Pieter Cullis, Jan Schuemann and Devika B. Chithrani
    Citation: Cancer Nanotechnology 2019 10:1
  46. Development of biocompatible multifunctional polymeric drug carriers is crucial in modern pharmaceutics aimed to create “smart” drugs. The high potential of the PEGylated comb-like polymeric nanocarrier (PNC) ...

    Authors: Lesya Kobylinska, Igor Patereha, Natalia Finiuk, Natalia Mitina, Anna Riabtseva, Igor Kotsyumbas, Rostyslav Stoika, Alexander Zaichenko and Sandor G. Vari
    Citation: Cancer Nanotechnology 2018 9:11

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