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  1. Five year survival for metastatic melanoma (MM) is very low at <10%. Therapeutic options have been limited secondary to systemic toxicity. As a result there has been a growing movement towards developing targe...

    Authors: Sameer Kaiser, Maximilian B MacPherson, Ted A James, Albert Emery, Page Spiess, Albert van der Vliet, Christopher C Landry and Arti Shukla

    Citation: Cancer Nanotechnology 2015 6:1

    Content type: Research

    Published on:

  2. Encapsulation of drugs in nanoparticles can enhance the accumulation of drugs in tumours, reduce toxicity toward healthy tissue, and improve pharmacokinetics compared to administration of free drug. To achieve...

    Authors: Sofie Snipstad, Sara Westrøm, Yrr Mørch, Mercy Afadzi, Andreas KO Åslund and Catharina de Lange Davies

    Citation: Cancer Nanotechnology 2014 5:8

    Content type: Research

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    The Erratum to this article has been published in Cancer Nanotechnology 2015 6:3

  3. Recently, the addition of nanoparticles (NPs) has been proposed as a new strategy to enhance the effect of radiotherapy particularly in the treatment of aggressive tumors such as glioblastoma. The physical pro...

    Authors: Lenka Štefančíková, Erika Porcel, Pierre Eustache, Sha Li, Daniela Salado, Sergio Marco, Jean-Luc Guerquin-Kern, Matthieu Réfrégiers, Olivier Tillement, François Lux and Sandrine Lacombe

    Citation: Cancer Nanotechnology 2014 5:6

    Content type: Research

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  4. Gold nanoparticles (GNPs), have been demonstrated as effective preclinical radiosensitising agents in a range of cell models and radiation sources. These studies have also highlighted difficulty in predicted c...

    Authors: Laura E Taggart, Stephen J McMahon, Fred J Currell, Kevin M Prise and Karl T Butterworth

    Citation: Cancer Nanotechnology 2014 5:5

    Content type: Research

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  5. AGuIX nanoparticles are formed of a polysiloxane network surrounded by gadolinium chelates. They present several characteristics. They are easy to produce, they present very small hydrodynamic diameters (<5 nm...

    Authors: Géraldine Le Duc, Stéphane Roux, Amandine Paruta-Tuarez, Sandrine Dufort, Elke Brauer, Arthur Marais, Charles Truillet, Lucie Sancey, Pascal Perriat, François Lux and Olivier Tillement

    Citation: Cancer Nanotechnology 2014 5:4

    Content type: Research

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  6. The possibility of developing novel contrast imaging agents for cancer cellular labelling and fluorescence imaging applications were explored using silica-coated cadmium selenide (CdSe) quantum dots (QDs). The...

    Authors: Muthunayagam Vibin, Ramachandran Vinayakan, Annie John, Francis Boniface Fernandez and Annie Abraham

    Citation: Cancer Nanotechnology 2014 5:1

    Content type: Research

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  7. In this work matrix based nanoparticulate polymer systems have been designed using the diacrylate derivative of the well-known biocompatible polymer, poly(ethylene glycol) (PEG). This has been crosslinked usin...

    Authors: Dipti Kakkar Thukral, Shweta Dumoga, Shelly Arora, Krishna Chuttani and Anil K Mishra

    Citation: Cancer Nanotechnology 2014 5:3

    Content type: Research

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  8. The aim of the present study was the direct covalent coupling of the epidermal growth factor receptor (EGFR)-specific monoclonal antibody (mAb) to the surface of poly(lactide)-co-glycolide (PLGA)-polyethylene ...

    Authors: Sahil Aggarwal, Swati Gupta, Dilrose Pabla and R. S. R. Murthy

    Citation: Cancer Nanotechnology 2013 4:46

    Content type: Original Paper

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  9. Green synthesis of silver nanoparticles was carried out using the aqueous extract of Alternanthera sessilis under various experimental conditions. The aqueous extract of Alternanthera sessilis showed significant ...

    Authors: M. Jannathul Firdhouse and P. Lalitha

    Citation: Cancer Nanotechnology 2013 4:45

    Content type: Original Paper

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  10. Cisplatin is used to treat a variety of tumors, but dose-limiting toxicities or intrinsic and acquired resistance limit its application in many types of cancer including breast. Cisplatin was attached to silic...

    Authors: Chandrababu Rejeeth, Tapas C. Nag and Soundarapandian Kannan

    Citation: Cancer Nanotechnology 2013 4:43

    Content type: Original Paper

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  11. A nanorobot is defined as any smart structure which is capable of actuation, sensing, manipulation, intelligence, and swarm behavior at the nanoscale. In this study, we designed an intelligent system using fuz...

    Authors: Mark Fletcher, Mohammad Biglarbegian and Suresh Neethirajan

    Citation: Cancer Nanotechnology 2013 4:44

    Content type: Original Paper

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  12. The aim of our study was to prepare multifunctional, biocompatible nanoparticles for site-specific drug delivery. Hydrophilic nanoparticles with surface-adorned amine, carboxyl, or aldehyde groups, to be later...

    Authors: Sourav Chattopadhyay, Sandeep Kumar Dash, Totan Ghosh, Debasis Das, Panchanan Pramanik and Somenath Roy

    Citation: Cancer Nanotechnology 2013 4:42

    Content type: Original Paper

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  13. As the nano revolution unfolds, it is imperative to integrate nanoscience and medicine. The secret gleaned from nature have led to the generation of biogenic technologies for the fabrication of advanced nanoma...

    Authors: Ravi Geetha, Thirunavukkarasu Ashokkumar, Selvaraj Tamilselvan, Kasivelu Govindaraju, Mohamed Sadiq and Ganesan Singaravelu

    Citation: Cancer Nanotechnology 2013 4:40

    Content type: Original Paper

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  14. Photothermal therapy (PTT) for cancer treatment is the use of heat between 41 and 45 °C to damage cancer cells. As a new type of transducer agent for PTT of cancer, CuS nanoparticles have several advantages. T...

    Authors: Chang Yang, Lun Ma, Xiaoju Zou, Guangya Xiang and Wei Chen

    Citation: Cancer Nanotechnology 2013 4:39

    Content type: Original Paper

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  15. Limited efficacy of current first-line treatment for leukemia calls attention for further development of efficient strategies. Recently, much attention has been given to nanoparticle-based drug delivery system...

    Authors: Tanmoy Bhowmik, Partha Pratim Saha, Anjan Dasgupta and Antony Gomes

    Citation: Cancer Nanotechnology 2013 4:36

    Content type: Original Paper

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  16. Normal micelle microemulsion method was utilized for fabrication of organically modified silica (ORMOSIL) nanoparticles. The void and dye-doped nanoparticles were synthesized in nonpolar core of two different ...

    Authors: Vahid Shirshahi, Fereshteh Shamsipour, Amir Hassan Zarnani, Javad Verdi and Reza Saber

    Citation: Cancer Nanotechnology 2013 4:35

    Content type: Original Paper

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  17. Intratumoral and intralesional administration of anticancer drugs in gels and implantable formulations is gaining much importance on account of its advantage of site-specific delivery with highly dependable fr...

    Authors: Tanya Vohra, Inderpreet Kaur, Hemraj Heer and Rayasa Ramachandra Murthy

    Citation: Cancer Nanotechnology 2013 4:32

    Content type: Original Paper

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  18. Urinary tract infection (UTI) is a predominant condition in prostate cancer patients. Escherichia coli ORN178 (EC-178) is the uropathogen that causes recurrent infection by binding specifically to adhesins of pro...

    Authors: Pallavi Vedantam, George Huang and T. R. Jeremy Tzeng

    Citation: Cancer Nanotechnology 2013 4:33

    Content type: Original Paper

    Published on:

  19. Broad spectrum therapeutic potential of curcumin is usually hampered by its photodegradation and low bioavailability. Present investigation was designed with an objective to develop transferrin-mediated solid ...

    Authors: Rohit S. Mulik, Jukka Mönkkönen, Risto O. Juvonen, Kakasaheb R. Mahadik and Anant R. Paradkar

    Citation: Cancer Nanotechnology 2012 3:31

    Content type: Original Paper

    Published on:

  20. This article reports on the application of organically modified silica (ORMOSIL) nanoparticles as an efficient in vitro gene delivery system in the recent years. Based on that prime objective, the present stud...

    Authors: Chandrababu Rejeeth, Soundarapandian Kannan and Krishnasamy Muthuchelian

    Citation: Cancer Nanotechnology 2012 3:30

    Content type: Original Paper

    Published on:

  21. As systemic cancer therapies improve and are able to control metastatic disease outside the central nervous system, the brain is increasingly the first site of relapse. The blood–brain barrier (BBB) represents...

    Authors: Mi-Ran Choi, Rizia Bardhan, Katie J. Stanton-Maxey, Sunil Badve, Harikrishna Nakshatri, Keith M. Stantz, Ning Cao, Naomi J. Halas and Susan E. Clare

    Citation: Cancer Nanotechnology 2012 3:29

    Content type: Original Paper

    Published on:

  22. The development of smart nanoparticles that can exhibit the anti-cancer activity, introduces better efficacy and lower toxicity for treatment. The present study was aimed to evaluate the anti-cancer activity o...

    Authors: S. Chattopadhyay, S. P. Chakraborty, D. Laha, R. Baral, P. Pramanik and S. Roy

    Citation: Cancer Nanotechnology 2012 3:26

    Content type: Original Paper

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  23. PLGA nanoparticles, separately loaded with etoposide (ETN) and quercetin dihydrate (QDN), were prepared by adapting the solvent diffusion (nanoprecipitation) technique. The effect of formulation variables such...

    Authors: Smita Pimple, Arehalli S. Manjappa, Mukesh Ukawala and R. S. R. Murthy

    Citation: Cancer Nanotechnology 2012 3:27

    Content type: Original Paper

    Published on:

  24. Cancer is one of the leading causes of death in most parts of the world and is a very serious cause of concern particularly in developing countries. In this work, we prepared and evaluated the aptamer-labeled ...

    Authors: Athulya Aravind, Saino Hanna Varghese, Srivani Veeranarayanan, Anila Mathew, Yutaka Nagaoka, Seiki Iwai, Takahiro Fukuda, Takashi Hasumura, Yasuhiko Yoshida, Toru Maekawa and D. Sakthi Kumar

    Citation: Cancer Nanotechnology 2012 3:24

    Content type: Original Paper

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  25. In the present study, poly(ethylene glycol)-b-poly(ε-caprolactone) micelles loaded with etoposide (ETO) were formulated and further conjugated with pentapeptide Glu-Ile-Leu-Asp-Val (EILDV) to target α4β1 integrin...

    Authors: Mukesh Ukawala, Tushar Rajyaguru, Kiran Chaudhari, A. S. Manjappa, R. S. R. Murthy and Rajiv Gude

    Citation: Cancer Nanotechnology 2011 2:23

    Content type: Original Paper

    Published on:

  26. The remarkable health benefits of the chemical cocktails occluded within Vites vinefera (grapes) have been broadly used as dietary supplements and as natural pharmaceuticals in the treatment of various diseases i...

    Authors: Kanchana Amarnath, Nina Liza Mathew, Jayshree Nellore, Chagam Reddy Venkat Siddarth and Jayanthi Kumar

    Citation: Cancer Nanotechnology 2011 2:22

    Content type: Original Paper

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  27. In this paper, we have proposed a simple method to covalently conjugate biotin to magnetic nanoparticles, which can be targeted to the tumour sites by using pretargeting approach with avidin or streptavidin. M...

    Authors: Ram Prakash Chauhan, Gurjaspreet Singh, Sweta Singh, Narmada Bag, Manoj Patra, S. R. Vadera, Anil K. Mishra and Rashi Mathur

    Citation: Cancer Nanotechnology 2011 2:21

    Content type: Original Paper

    Published on:

  28. Growth experiments of transplanted malignant tumors in the presence of water-soluble C60 fullerenes were performed on groups of mice. It was found that C60 fullerenes efficiently inhibit the growth of transplante...

    Authors: S. V. Prylutska, A. P. Burlaka, P. P. Klymenko, I. I. Grynyuk, Yu. I. Prylutskyy, Ch. Schütze and U. Ritter

    Citation: Cancer Nanotechnology 2011 2:20

    Content type: Original Paper

    Published on:

  29. Photodynamic therapy (PDT) is a promising treatment methodology whereby diseased cells and tissues are destroyed by reactive oxygen species (ROS) by using a combination of light and photosensitizers (PS). The ...

    Authors: Krishnamoorthy Karthikeyan, Anish Babu, Sang-Jae Kim, Ramachandran Murugesan and Kadarkaraithangam Jeyasubramanian

    Citation: Cancer Nanotechnology 2011 2:19

    Content type: Original Paper

    Published on:

  30. Celecoxib, a selective cyclooxygenase-2 inhibitor, has shown potential anticancerous activity against majority of solid tumors especially on patients with colon cancer. However, associations of serious side ef...

    Authors: Venkatesan Perumal, Shubhadeep Banerjee, Shubasis Das, R. K. Sen and Mahitosh Mandal

    Citation: Cancer Nanotechnology 2011 2:17

    Content type: Original Paper

    Published on:

  31. Biofunctionalized gold and silver nanoparticles synthesized using different plant extracts of guava and clove in vitro anti-cancer efficacy against four different cancer cell lines human colorectal adenocarcin...

    Authors: Deshpande Raghunandan, Bhat Ravishankar, Ganachari Sharanbasava, D. Bedre Mahesh, Vasanth Harsoor, Manjunath S. Yalagatti, M. Bhagawanraju and A. Venkataraman

    Citation: Cancer Nanotechnology 2011 2:14

    Content type: Original Paper

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  32. The present study discusses evaluation of pullulan-functionalized doxorubicin nanoparticles for asialoglycoprotein receptor-mediated uptake in the Hep G2 cell line. Doxorubicin hydrochloride (DOX) nanoparticle...

    Authors: Swati A. Guhagarkar, Sharmila B. Majee, Abdul Samad and Padma V. Devarajan

    Citation: Cancer Nanotechnology 2011 2:12

    Content type: Original Paper

    Published on:

  33. The conventional chemotherapeutic agents used in the treatment of human malignancies are directed nonspecifically against both malignant and nonmalignant cells, often limiting their efficacy with having seriou...

    Authors: Hirak Kumar Patra, Anjan Kr. Dasgupta, Sounik Sarkar, Indranil Biswas and Arnab Chattopadhyay

    Citation: Cancer Nanotechnology 2011 2:11

    Content type: Original Paper

    Published on:

  34. To develop a suitable formulation with high entrapment efficiency, etoposide-loaded poly(lactide-co-glycolide) nanoparticles (NPs) were formulated by single emulsion-solvent evaporation method by changing differe...

    Authors: Moutushy Mitra, Fahima Dilnawaz, Ranjita Misra, Anju Harilal, Rama Shenkar Verma, Sanjeeb K. Sahoo and Subramanian Krishnakumar

    Citation: Cancer Nanotechnology 2010 2:10

    Content type: Original Paper

    Published on:

    The Erratum to this article has been published in Cancer Nanotechnology 2011 2:13

  35. Targeted nanoparticles have the potential to deliver a large drug payload specifically to cancer cells. Targeting requires that a ligand on the nanoparticle surface interact with a specific membrane receptor o...

    Authors: Honglin Jin, Jonathan F. Lovell, Juan Chen, Kenneth Ng, Weiguo Cao, Lili Ding, Zhihong Zhang and Gang Zheng

    Citation: Cancer Nanotechnology 2010 1:9

    Content type: Original Paper

    Published on:

  36. The present study was designed to explore the ability of polymeric nanoparticles to restore drug sensitivity to P-glycoprotein over-expressing cancer cells. A multidrug-resistant cell line 2780 AD and its sens...

    Authors: V. Bhardwaj, J. A. Plumb, J. Cassidy and M. N. V. Ravi Kumar

    Citation: Cancer Nanotechnology 2010 1:4

    Content type: Original Paper

    Published on:

  37. In this study, we report the preparation, luminescence, and targeting properties of folic acid-CdTe quantum dot conjugates. Water-soluble CdTe quantum dots were synthesized and conjugated with folic acid using...

    Authors: Preethi Suriamoorthy, Xing Zhang, Guiyang Hao, Alan G. Joly, Surya Singh, Marius Hossu, Xiankai Sun and Wei Chen

    Citation: Cancer Nanotechnology 2010 1:3

    Content type: Original Paper

    Published on:

  38. The application of nanomaterial in cancer treatment is promising and intriguing. Anti-tumor immunotherapy has the potential to significantly improve the prognosis of cancer treatment, though the efficacy of im...

    Authors: Zhao Sun, Wei Wang, Rui Wang, Jinhong Duan, Yan Hu, Jin Ma, Jiayan Zhou, Sishen Xie, Xin Lu, Zhaohui Zhu, Shuchang Chen, Yuanli Zhao, Haiyan Xu, Chen Wang and Xian-Da Yang

    Citation: Cancer Nanotechnology 2010 1:1

    Content type: Original Paper

    Published on:

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