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  1. Cisplatin (CP) is the first-line standard of care for bladder cancer. However, a significant percentage of advanced bladder cancer patients are ineligible to receive standard CP treatment, due to the drug’s to...

    Authors: Yoray Sharon, Menachem Motiei, Chen Tzror-Azankot, Tamar Sadan, Rachela Popovtzer and Eli Rosenbaum
    Citation: Cancer Nanotechnology 2023 14:72
  2. Newcastle disease virus (NDV) Lasota strain has proven oncolytic activity. One shortcoming associated with this treatment modality is the immune neutralization of the virus in body, mediated by natural killer ...

    Authors: Kousain Kousar, Faiza Naseer, Maisa S. Abduh, Sadia Anjum and Tahir Ahmad
    Citation: Cancer Nanotechnology 2023 14:71
  3. In the current treatment of non-small cell lung cancer (NSCLC), traditional chemotherapy causes high toxicity, so it is necessary to develop safe chemical drug delivery vehicles clinically. Chemotherapy monoth...

    Authors: Tiantian Tan, Yuxin Feng, Weimin Wang, Rongrong Wang, Liyan Yin, Yiying Zeng, Zhaowu Zeng and Tian Xie
    Citation: Cancer Nanotechnology 2023 14:70
  4. The use of nanocarriers to improve the targeting of treatment plays a key role in the treatment of many diseases, including cancer. This study was carried out to synthesize graphene oxide (GO) containing 6-gin...

    Authors: Angham Hakim Abdulzahra Al-Janabi, Nasim Hayati Roodbari and Masoud Homayouni Tabrizi
    Citation: Cancer Nanotechnology 2023 14:69
  5. Chlorin e6 trisodium salt (Ce6) is a newly developed hydrophilic photosensitizer designed to mediate anticancer photodynamic therapy (PDT). The response of different cancer types and strategies to boost antica...

    Authors: Sara A. Abdel Gaber, Herbert Stepp, Mahmoud H. Abdel Kader and Mika Lindén
    Citation: Cancer Nanotechnology 2023 14:67
  6. Owing to the complexity of cancer, a synergistic combination of chemotherapy and gene therapy can be a promising therapeutic strategy. This study aimed to use stem cell membrane (SCM)-camouflaged polydopamine ...

    Authors: Kunzhe Wu, Zhongsheng Zhou, Te Liu, Chunkang Liu, Xupeng Mu and Jinlan Jiang
    Citation: Cancer Nanotechnology 2023 14:66
  7. The in vivo anticancer potential of vincristine (VC) loaded, thiolated chitosan-based nanoformulation (NFs) with an outer hyaluronic acid (VC-loaded in TCs-HA) coating was studied in prostate cancer (PC) xenog...

    Authors: Faiza Naseer, Kousain Kousar, Maisa S. Abduh, Sadia Anjum and Tahir Ahmad
    Citation: Cancer Nanotechnology 2023 14:65

    The Correction to this article has been published in Cancer Nanotechnology 2023 14:68

  8. Triple-negative breast cancer (TNBC) remains a difficult breast cancer subtype to treat as it exhibits a particularly aggressive behavior. The dysregulation of distinct signaling pathways underlies this aggres...

    Authors: Vladimir Mulens-Arias, Yadileiny Portilla, Sonia Pérez-Yagüe, Raquel Ferreras-Martín, M. Elena Martín, Victor M. González and Domingo F. Barber
    Citation: Cancer Nanotechnology 2023 14:64
  9. Extracellular vesicles (EVs) have tremendous potential as nano/micron-sized drug delivery carriers. Their physical, chemical and biological characteristics distinguish them as unique carriers with specific ph...

    Authors: Hui Luo, Jing Jin, Jiajia Jin, Kecheng Lou, Hailan He, Shangzhi Feng, Fei Zeng and Junrong Zou
    Citation: Cancer Nanotechnology 2023 14:63
  10. The vascular endothelial growth factor receptor-2 (VEGFR-2) plays an important role in melanoma development and progression. Peptide vaccines have shown great potential in cancer immunotherapy by targeting VEG...

    Authors: Fatemeh Zahedipour, Parvin Zamani, Mohammad Mashreghi, Mojgan Astaneh, Mojtaba Sankian, Atefeh Amiri, Khadijeh Jamialahmadi and Mahmoud Reza Jaafari
    Citation: Cancer Nanotechnology 2023 14:62
  11. As a radiosensitizing agent in magnetic resonance imaging (MRI), gadolinium is disadvantageous in that it confers a rather high toxicity and low longitudinal comfort time (r1). We hypothesized that gadolinium whe...

    Authors: Azadeh Amraee, Zahra Alamzadeh, Rasoul Irajirad, Abolfazl Sarikhani, Habib Ghaznavi, Hossein Ghadiri Harvani, Seied Rabi Mahdavi, Sakine Shirvalilou and Samideh Khoei
    Citation: Cancer Nanotechnology 2023 14:61
  12. Gallic acid is a natural antioxidant present in many plants such as tea, sumac, gallnut and other plants. This naturally occurring gallic acid is known to exhibit auto-oxidation under certain conditions, gener...

    Authors: Ahmed. A. G. El-Shahawy, Esam M. Dief, S. I. El-Dek, A. A. Farghali and Fatma I. Abo El-Ela
    Citation: Cancer Nanotechnology 2023 14:60
  13. Using a chemotherapeutic agent, such as doxorubicin (DOX), with a natural agent, such as silibinin (Sili), is highly valuable to minimize systemic toxicity. However, Sili and DOX face disadvantages, such as lo...

    Authors: Maryamsadat Shahidi, Bibi Fatemeh Haghiralsadat, Omid Abazari, Mahdie Hemati, Parisa Dayati, Hossein Zarei Jaliani, Najmeh Sadat Hosseini Motlagh, Seyed Morteza Naghib and Ali Moradi
    Citation: Cancer Nanotechnology 2023 14:59
  14. Glioma is the most prevalent type of primary brain tumor, and glioblastoma multiforme (GBM) is the highest and most deadly type of primary central nervous system (CNS) tumor, affecting a significant number of ...

    Authors: Dongdong Liu, Xingliang Dai, Zhenchao Tao, Hu Zhou, Wenqing Hong, Haisheng Qian, Hongwei Cheng and Xianwen Wang
    Citation: Cancer Nanotechnology 2023 14:58
  15. The lack of efficacious treatments for clear cell renal cell carcinoma (ccRCC) has led to a poor 5-year survival rate. Here, we found that the expression of ADAM metallopeptidase with thrombospondin type 1 mot...

    Authors: Enyang Zhao, Bo Geng, Ran Tao, Bosen You, Yunli Liu, Wenbin Hou, Wanhui Wang, Changlin Wang and Xuedong Li
    Citation: Cancer Nanotechnology 2023 14:57
  16. Zinc oxide nanoparticles (ZnO NPs) have been known as a therapeutic agent and drug delivery system for treating various diseases, including infectious diseases and cancer. However, due to the low biocompatibil...

    Authors: Qing Zhou, Li Zhang, Yujiao Li, Jiao Wang, Xiaolu He, Jieyu Zhang, Youbei Qiao, Hong Wu and Lin Zhu
    Citation: Cancer Nanotechnology 2023 14:56
  17. Cancer stem cells (CSCs) are of great diagnostic importance due to their involvement in tumorigenesis, therapeutic resistance, metastasis and relapse.

    Authors: Solmaz Sadi, Balal Khalilzadeh, Mahdi Mahdipour, Fatemeh Sokouti Nasimi, Ibrahim Isildak, Soodabeh Davaran, Mohammad-Reza Rashidi and Farhad Bani
    Citation: Cancer Nanotechnology 2023 14:55
  18. Combining the power of magnetic guidance and the biological activities of stem cells transformed into biohybrid microrobots holds great promise for the treatment of several diseases including cancer.

    Authors: Rebekah Anamarie Gundersen, Tianyuan Chu, Kiana Abolfathi, Serap Gokcen Dogan, Phoebe Elizabeth Blair, Nyasha Nago, Michael Hamblin, Greg Nicholas Brooke, Ralf Michael Zwacka, Ali Kafash Hoshiar and Andrea Mohr
    Citation: Cancer Nanotechnology 2023 14:54
  19. Tumor hypoxia is an important factor for developing resistance to radiation therapy (RT) and presents a bleak prognosis in cancer patients undergoing treatment for RT resistant hepatocellular carcinoma. Here, ...

    Authors: Reju George Thomas, Subin Kim, Raveena Nagareddy, Veena Vijayan, Ansuja Mathew Pullickal, Mee Sun Yoon, In Kyu Park and Yong Yeon Jeong
    Citation: Cancer Nanotechnology 2023 14:53
  20. The accurate diagnosis and treatment of cancer cell lesions need a high standard of detection technology. Fluorescent probes to perform cancer biomarker detection have become a popular research issue. However,...

    Authors: Yue He, Hongtao Rao, JingJing Wang, Ying Wu, Caiqin Han, Changchun Yan, Hunter Temple, Le Zhang, Wei Chen and Ying Liu
    Citation: Cancer Nanotechnology 2023 14:52
  21. Blocking the binding of PD-1/PD-L1 has become an effective strategy in inhibition of tumor immune escape. At present, it mainly depends on the employment of macromolecular antibodies, which target PD-1/PD-L1 p...

    Authors: Wenwen Ji, Bei Zhang, Xuetong Sun, Lijuan Ma, Xiangying Zhang, Wenhui Qian, Wenjuan Fu, Jianting Li and Dong Zhu
    Citation: Cancer Nanotechnology 2023 14:51
  22. Tumor angiogenesis, immunosuppression, and progression are all closely correlated with the tumor microenvironment (TME). Immune evasion is supported by both M2 phenotype tumor-associated macrophages (TAMs) and...

    Authors: Hongsheng Wang, Xinmeng Jin, Yinghua Gao, Xin He, Yiming Xu, Haoran Mu, Yafei Jiang, Zhuoying Wang, Chen Yu, Tao Zhang, Yingqi Hua, Zhengdong Cai, Jing Xu, Xiaojun Ma and Wei Sun
    Citation: Cancer Nanotechnology 2023 14:50
  23. This study aimed to overcome the poor solubility of pterostilbene (PTS) by developing promising reconstituted proethoniosomes (PENs). The reconstituted PENs loaded with PTS were fabricated according to a 23 facto...

    Authors: Nemany A. N. Hanafy, Reham H. Abdelbadea, Abdelaziz E. Abdelaziz and Eman A. Mazyed
    Citation: Cancer Nanotechnology 2023 14:49
  24. Tyrosine kinase inhibitors (TKI) have been highlighted for the therapy of non-small-cell lung cancer (NSCLC), due to their capability of efficiently blocking signal pathway of epidermal growth factor receptor ...

    Authors: Mingwei Wang, Haiyan Huang, Zilong Zhong, Xinyue Chen, Yuan Fang, Shenxin Chen, Zhiyao Qi, Danrong Yang, Junyou Wang and Wei Bian
    Citation: Cancer Nanotechnology 2023 14:48
  25. Gadolinium-based nanoparticles (GdNPs) are clinically used agents to increase the radiosensitivity of tumor cells. However, studies on the mechanisms and biological modeling of GdNP radio-enhancement are still...

    Authors: Jianan Wu, Xiaohan Xu, Ying Liang, Tujia Chen, Enzhuo Quan and Luhua Wang
    Citation: Cancer Nanotechnology 2023 14:47
  26. A novel magnetic-targeted pH-responsive intelligent drug carrier based on hollow mesoporous structured NiFe2O4 nanospheres was designed and developed for potential anticancer treatment in the present study. The h...

    Authors: Qing Qi, Hui Zhang, Mengru Liu, Shujing Qi, Zhongchao Huo, Yingying Ma, Zhongqiang Zhang, Yongchang Lu, Xiongwei Qi, Shuai Han and Guangshuo Wang
    Citation: Cancer Nanotechnology 2023 14:46
  27. Developing high-performance sensing frameworks for diagnosing anaplastic changes is the subject of debate. The lack of on-time diagnosis in patients with suspicious cancers can affect the prognosis and surviva...

    Authors: Hassan Nasrollahpour, Balal Khalilzadeh, Reza Rahbarghazi, Nevin Erk, Mohammad-Reza Rashidi and Abdolhossein Naseri
    Citation: Cancer Nanotechnology 2023 14:45
  28. In the present study, a magnetohyperthermia (MH)-based therapy is introduced as an effective treatment for deep-seated tumors especially glioma, which combines the magnetothermal effect and the reactive oxygen...

    Authors: Roghayeh Sheervalilou, Samideh Khoei, Sepideh Khoee, Milad Shirvaliloo, Elaheh Sadri, Sakine Shirvalilou and Mina Goudarzi
    Citation: Cancer Nanotechnology 2023 14:44
  29. Bone metastasis is the main cause of death in patients with prostate cancer (PCa), but there lacks effective treatment method. Immunotherapy shows new hopes for bone metastatic PCa patients, while the efficacy...

    Authors: Shu Huang, Jun Yuan, Yong Xie, Kai Qing, Zeya Shi, Guanyu Chen, Jie Gao, Haoxiang Tan and Wenhu Zhou
    Citation: Cancer Nanotechnology 2023 14:43
  30. Nano-Zinc oxide (Nano-ZnO) has been increasingly applied in agriculture, industry and biomedicine. However, the genotoxic effects of Nano-ZnO and the underlying mechanisms remain incompletely clear.

    Authors: Meiling Zhou, Liang Xiao, Jing Jin, Yin Wang, Peiyu Guo, Jinhua Luo, Magdalena Skonieczna and Ruixue Huang
    Citation: Cancer Nanotechnology 2023 14:42
  31. For the treatment of triple-negative breast cancer (TNBC), without expression of estrogen, progesterone and HER2 receptors, specific treatment guideline is still under criticism, especially in tumor hypoxia. B...

    Authors: Majid Sharifi, Rasoul Kheradmandi and Morteza Alizadeh
    Citation: Cancer Nanotechnology 2023 14:41
  32. Fenton reaction-based chemodynamic therapy (CDT) is regarded as a highly tumor-specific treatment modality due to its intrinsic tumor microenvironment (TME)-specific targeting properties, such as high amounts ...

    Authors: Laya Khoshtabiat, Azadeh Meshkini and Maryam M. Matin
    Citation: Cancer Nanotechnology 2023 14:40
  33. Increasing evidence indicates that radiotherapy (RT) has synergistic inhibitory efficiency with immunotherapy agents in multiple cancers and enhances abscopal effects by regulating the innate immune response, ...

    Authors: Dehua Lu, Yanming Xu, Xiaodong Yang, Ying Li, Mengqing Li, Yuanyuan Zheng, Yuenan Wang, Weihu Wang, Shubin Wang, Jing Gao and Yajie Liu
    Citation: Cancer Nanotechnology 2023 14:39
  34. Overwhelming Fe accumulation in tumor arouses strong oxidative stress. To benefit the cancer patients, Fe(II) delivered by carbon nanoparticles-Fe(II) complex (CNSI-Fe) should be visualized to ensure the succe...

    Authors: Ping Xie, Yuanfang Huang, Kexin Tang, Xian Wu, Cheng Zeng, Sheng-Tao Yang and Xiaohai Tang
    Citation: Cancer Nanotechnology 2023 14:38
  35. Colorectal cancer (CRC) is the third most diagnosed tumor worldwide, with a very high mortality rate, second only to lung cancer. Current treatments, such as surgery, chemotherapy or radiotherapy, are not effe...

    Authors: Luisa Racca, Giada Rosso, Marco Carofiglio, Sharmila Fagoonee, Giulia Mesiano, Fiorella Altruda and Valentina Cauda
    Citation: Cancer Nanotechnology 2023 14:37
  36. Cationic dyes are widely used as biomarkers for optical imaging. However, most of these are hydrophobic and cannot be employed in vivo without chemical conjugation or modification. Herein, we report for the fi...

    Authors: Nian Liu, Vipul Gujrati, Juan Pablo Fuenzalida Werner, Kanuj Mishra, Pia Anzenhofer, Andre C. Stiel, Gabriele Mettenleiter, Annette Feuchtinger, Axel Walch and Vasilis Ntziachristos
    Citation: Cancer Nanotechnology 2023 14:36
  37. Ti3C2 is a type of transition metal carbides and nitrides (MXenes) with high light-to-heat conversion efficiency property, which has been widely used in cancer treatment recently. In fact, active targeting delive...

    Authors: Zhiqiang Bai, Lu Zhao, Haidi Feng, Zhihui Xin, Chaoyu Wang, Zhixiong Liu, Maozhong Tian, Haifei Zhang, Yunfeng Bai and Feng Feng
    Citation: Cancer Nanotechnology 2023 14:35
  38. Tumor microparticles (T-MPs) are considered as a tumor vaccine candidate. Although some studies have analyzed the mechanism of T-MPs as tumor vaccine, we still lack understanding of how T-MPs stimulate a stron...

    Authors: Weiwei Sun, Lili Dai, Yuqing Cao, Pengtao Pan, Lijuan Zhi, Xinke Wang, Xinzhong Yuan, Zi Gao, Sheng Guo, Guoyan Liu, Junlei Yin, Liangliang Xie, Liping Wang, Yanling Wang, Wensheng Li, Hong Li…
    Citation: Cancer Nanotechnology 2023 14:34
  39. Radiotherapy is a major therapeutic modality for locally advanced head and neck cancer. However, the effectiveness of radiotherapy is hindered by resistance mechanisms, most notably hypoxia, leading to unfavou...

    Authors: Jie Feng, Varun Pathak, Niall M. Byrne, Tongchuan Wang, Cancan Yin, Reinhold J. Medina and Jonathan A. Coulter
    Citation: Cancer Nanotechnology 2023 14:33
  40. Colorectal malignant cells (CRC) are one of the world’s main causes of cancer mortality and morbidity. Notwithstanding the plenty of anti-CRC therapeutics, its prognosis remains not selective owing to cancer r...

    Authors: Ahmed A. Abd-Rabou, Ahmed M. Abdelaziz, Olfat G. Shaker and Ghada Ayeldeen
    Citation: Cancer Nanotechnology 2023 14:32
  41. Multiwalled carbon nanotubes (MWCNTs) are being widely investigated in multiple biomedical applications including, and not limited to, drug delivery, gene therapy, imaging, biosensing, and tissue engineering. ...

    Authors: Seung Soo Lee, Fatma Oudjedi, Andrew G. Kirk, Miltiadis Paliouras and Mark A. Trifiro
    Citation: Cancer Nanotechnology 2023 14:31
  42. Cancer is a major threat to human health; thus, early detection is imperative for successful management. Rapid diagnosis can be achieved by imaging primary (subcutaneous) tumors using fluorophores conjugated w...

    Authors: Sulaxna Pandey, Prakash Choudhary, Virendra Gajbhiye, Sachin Jadhav and Dhananjay Bodas
    Citation: Cancer Nanotechnology 2023 14:30
  43. Head and neck squamous cell carcinoma (SCC) is one of the most prevalent and deadly cancers worldwide. Even though surgical approaches, radiation therapy, and therapeutic agents are commonly used, the prognosi...

    Authors: Alberto Juan, Carmen Segrelles, Almudena del Campo-Balguerías, Iván Bravo, Ignacio Silva, Jorge Peral, Alberto Ocaña, Pilar Clemente-Casares, Carlos Alonso-Moreno and Corina Lorz
    Citation: Cancer Nanotechnology 2023 14:29
  44. Lung cancer is the leading cause of cancer mortality. As a heterogeneous disease, it has different subtypes and various treatment modalities. In addition to conventional surgery, radiotherapy and chemotherapy,...

    Authors: Yifan Liu, Wenxu Cheng, HongYi Xin, Ran Liu, Qinqi Wang, Wenqi Cai, Xiaochun Peng, Fuyuan Yang and HongWu Xin
    Citation: Cancer Nanotechnology 2023 14:28
  45. Chemotherapy resistance remains a major cause of therapeutic failure in gastric cancer. The combination of genetic material such as interference RNAs (iRNAs) to silence cancer-associated genes with chemotherap...

    Authors: Sofia Nascimento dos Santos, Dino Seigo Gushiken Junior, Jhonatas Pedrosa Marim Pereira, Natália Miranda Iadocicco, André Henrique Silva, Tatielle do Nascimento, Luís Alberto Pereira Dias, Flávia Rodrigues de Oliveira Silva, Eduardo Ricci-Junior, Ralph Santos-Oliveira and Emerson Soares Bernardes
    Citation: Cancer Nanotechnology 2023 14:26
  46. Intraperitoneal metastasis is one of the major causes of the high mortality rate of ovarian cancer. Bufalin (BU) is an effective component of the traditional Chinese medicine Chansu that exerts antitumor effec...

    Authors: Lan Xu, Shuli Ma, Bozhen Fan, Zeting Yuan and Peihao Yin
    Citation: Cancer Nanotechnology 2023 14:25
  47. Anethole (Ant) is a herbal compound with unique properties, which is limited in its clinical use due to its low solubility in aqueous solutions. Therefore, in this study, albumin nanocarrier modified with chit...

    Authors: Farzaneh Sadeghzadeh, Hasti Nasiraei Haghighi, Mahdiyeh Ghiyamati, Fateme Hajizadenadaf and Masoud Homayouni Tabrizi
    Citation: Cancer Nanotechnology 2023 14:24
  48. The presented research concerns the preparation of polymer nanoparticles (PNPs) for the delivery of doxorubicin. Several block and statistical copolymers, composed of ketoester derivative, N-isopropylacrylamide, ...

    Authors: Paweł Misiak, Katarzyna Niemirowicz-Laskowska, Karolina H. Markiewicz, Przemysław Wielgat, Izabela Kurowska, Robert Czarnomysy, Iwona Misztalewska-Turkowicz, Halina Car, Krzysztof Bielawski and Agnieszka Z. Wilczewska
    Citation: Cancer Nanotechnology 2023 14:23

Annual Journal Metrics

  • Citation Impact 2023
    Journal Impact Factor: 4.5
    5-year Journal Impact Factor: 5.1
    Source Normalized Impact per Paper (SNIP): 0.723
    SCImago Journal Rank (SJR): 0.671

    Speed 2023
    Submission to first editorial decision (median days): 6
    Submission to acceptance (median days): 93

    Usage 2023
    Downloads: 328,851
    Altmetric mentions: 109