|
IC50 (nM)
|
---|
A2780
|
2780 AD
|
---|
24 h
|
24 h
|
72 h
|
---|
Blank nanoparticles
|
1,774 ± 129
|
–
|
3,175 ± 79
|
Paclitaxel
|
2.26 ± 0.91
|
5,240 ± 637
|
2,013 ± 73
|
Paclitaxel nanoparticles
|
0.30 ± 0.03
|
1,661 ± 89
|
903 ± 49
|
- Sensitivity is expressed as the IC50 (mean±SEM of three estimations) defined as the concentration of drug required to reduce the absorbance of the wells to 50% of that of the control untreated cells