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  1. Lung cancer is one of the most frequently diagnosed cancers all over the world and is also one of the leading causes of cancer-related mortality. The main treatment option for small cell lung cancer, conventio...

    Authors: Monika Ruzycka-Ayoush, Patrycja Kowalik, Agata Kowalczyk, Piotr Bujak, Anna M. Nowicka, Maria Wojewodzka, Marcin Kruszewski and Ireneusz P. Grudzinski

    Citation: Cancer Nanotechnology 2021 12:8

    Content type: Research

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  2. Magnetic fluid hyperthermia (MFH) is a successful nanotechnology application in recent decade where a biocompatible magnetic fluid is used to kill cancer cells in a controlled heating using AC magnetic field. ...

    Authors: Anand Bhardwaj, Neeraj Jain and Kinnari Parekh

    Citation: Cancer Nanotechnology 2021 12:7

    Content type: Research

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  3. The skin is both a target and a potential conduit for the delivery of drugs, but its cornified cell layer resists penetration by most molecules. This study investigated the potential of superparamagnetic iron ...

    Authors: Vanisri Raviraj, Binh T. T. Pham, Byung J. Kim, Nguyen T. H. Pham, Lai F. Kok, Nicole Painter, Naomi C. Delic, Stephen K. Jones, Brian S. Hawkett and J. Guy Lyons

    Citation: Cancer Nanotechnology 2021 12:6

    Content type: Research

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  4. Despite advances in glioblastoma (GBM) treatments, current approaches have failed to improve the overall survival of patients. The oncogene BMI-1, a core member of the polycomb group proteins, is a potential n...

    Authors: Elham Poonaki, Fatemeh Ariakia, Mohammad Jalili-Nik, Mehdi Shafiee Ardestani, Gholamhossein Tondro, Fariborz Samini, Sepideh Ghasemi, Sajad Sahab-Negah and Ali Gorji

    Citation: Cancer Nanotechnology 2021 12:5

    Content type: Research

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  5. In this study, we report on the synthesis, imaging, and radiosensitizing properties of ultrasmall β-NaGdF4:Yb50% nanoparticles as a multifunctional theranostic platform. The synthesized nanoparticles act as poten...

    Authors: Jossana A. Damasco, Tymish Y. Ohulchanskyy, Supriya Mahajan, Guanying Chen, Ajay Singh, Hilliard L. Kutscher, Haoyuan Huang, Steven G. Turowski, Joseph A. Spernyak, Anurag K. Singh, Jonathan F. Lovell, Mukund Seshadri and Paras N. Prasad

    Citation: Cancer Nanotechnology 2021 12:4

    Content type: Research

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  6. Here, we examined the tumoricidal effect of Gemini surfactant nanoparticles enriched with curcumin on 3D spheroid HT-29 cells. The delivery of curcumin and other phytocompounds to the tumor niche is an importa...

    Authors: Zohre Zibaei, Esmaeil Babaei, Arezoo Rezaie Nezhad Zamani, Reza Rahbarghazi and Hewa Jalal Azeez

    Citation: Cancer Nanotechnology 2021 12:3

    Content type: Research

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  7. The extracellular matrix (ECM) is a mosaic of various structural and functional proteins that cooperate with the cell, regulate adhesion, and consequently manage its further fate. Liver destruction is accompan...

    Authors: Malwina Sosnowska, Marta Kutwin, Barbara Strojny, Piotr Koczoń, Jarosław Szczepaniak, Jaśmina Bałaban, Karolina Daniluk, Sławomir Jaworski, André Chwalibog, Wiesław Bielawski and Ewa Sawosz

    Citation: Cancer Nanotechnology 2021 12:2

    Content type: Research

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  8. Ovarian cancer is one of the deadliest gynecological malignancies. While the overall survival of ovarian cancer patients has slightly improved in recent years in the developed world, it remains clinically chal...

    Authors: Md. Nazir Hossen, Chandra Kumar Elechalawar, Virginie Sjoelund, Kathleen Moore, Robert Mannel, Resham Bhattacharya and Priyabrata Mukherjee

    Citation: Cancer Nanotechnology 2021 12:1

    Content type: Research

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  9. The present study aims to develop a nanoparticle encapsulating doxorubicin (DOX) and programmed death-ligand 1 (PD-L1) siRNA and evaluate its anti-tumor effects on hepatoma carcinoma (HCC).

    Authors: Hanzhang Zhu, Weijiang Zhou, Yafeng Wan, Ke Ge, Jun Lu and Changku Jia

    Citation: Cancer Nanotechnology 2020 11:15

    Content type: Research

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  10. Amphiphilic block copolymers used as nanomicelle drug carriers can effectively overcome poor drug solubility and specificity issues. Hence, these platforms have a broad applicability in cancer treatment. In th...

    Authors: S. Pisano, X. Wang, J. Garcia-Parra, A. Gazze, K. Edwards, V. Feltracco, Y. Hu, L. He, D. Gonzalez, L. W. Francis, R. S. Conlan and C. Li

    Citation: Cancer Nanotechnology 2020 11:14

    Content type: Research

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  11. Breast cancer is therapeutically very challenging to treat as it has the main four known genetic alterations, which result in the existence of several phenotypes leading to the difference in the mode of therap...

    Authors: Sara Al Tamimi, Sarmadia Ashraf, Tahir Abdulrehman, Aijaz Parray, Said A. Mansour, Yousef Haik and Shahnaz Qadri

    Citation: Cancer Nanotechnology 2020 11:13

    Content type: Research

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  12. Breast cancer is a major cause of cancer-associated deaths in the United States. It was estimated that 12% of women in the U.S. will develop invasive breast cancer in their lifetime. The human epidermal growth...

    Authors: Bryan E. White, Molly K. White, Het Adhvaryu, Issam Makhoul, Zeid A. Nima, Alexandru S. Biris and Nawab Ali

    Citation: Cancer Nanotechnology 2020 11:12

    Content type: Review

    Published on:

  13. Breast cancer (BC), as the most widely recognized disease in women worldwide, represents about 30% of all cancers impacting women. This study was aimed to synthesize Cu2O nanoparticles from the cystoseira myrica ...

    Authors: Parisa Taherzadeh-Soureshjani and Mohammad Chehelgerdi

    Citation: Cancer Nanotechnology 2020 11:11

    Content type: Research

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  14. Cockle shell-derived aragonite calcium carbonate nanoparticles (CACNP) have demonstrated prospect as nano-sized drug carriers for targeting cancer cells. CACNP is biocompatible, biodegradable and its biomateri...

    Authors: Kehinde Muibat Ibiyeye, Sherifat Banke Idris and Abu Bakar Zakaria Zuki

    Citation: Cancer Nanotechnology 2020 11:10

    Content type: Review

    Published on:

  15. The AGuIX® (NH TherAguix) nanoparticle has been developed to enhance radiotherapy treatment and provide strong MR contrast. These two properties have previously been investigated separately and progressed to clin...

    Authors: H. L. Byrne, G. Le Duc, F. Lux, O. Tillement, N. M. Holmes, A. James, U. Jelen, B. Dong, G. Liney, T. L. Roberts and Z. Kuncic

    Citation: Cancer Nanotechnology 2020 11:9

    Content type: Research

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  16. Successful integration of nanotechnology into the current paradigm of cancer therapy requires proper understanding of the interface between nanoparticles (NPs) and cancer cells, as well as other key components...

    Authors: Kyle Bromma, Aaron Bannister, Antonia Kowalewski, Leah Cicon and Devika B. Chithrani

    Citation: Cancer Nanotechnology 2020 11:8

    Content type: Research

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  17. Doxorubicin-loaded hollow gold nanospheres (Dox@HAuNS) are a promising technology for simultaneous trans-arterial tumor-targeted chemotherapy delivery and thermal ablation. We evaluated the efficacy of intra-a...

    Authors: Rahul A. Sheth, Xiaoxia Wen, Junjie Li, Marites P. Melancon, Xin Ji, Y. Andrew Wang, Cheng-Hui Hsiao, Diana S.-L. Chow, Elizabeth M. Whitley, Chun Li and Sanjay Gupta

    Citation: Cancer Nanotechnology 2020 11:6

    Content type: Research

    Published on:

  18. The aim of this study was to compare contrast enhancement of Magnevist® (gadopentate dimeglumine (Mag)) to that of PEGylated Magnevist®-loaded liposomal nanoparticles (Mag-Lnps) in pancreatic cancer patient-deriv...

    Authors: Kevin Affram, Taylor Smith, Shannon Helsper, Jens T. Rosenberg, Bo Han, Jose Trevino and Edward Agyare

    Citation: Cancer Nanotechnology 2020 11:5

    Content type: Research

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  19. Nanotechnology is a frequent treatment for cancer. Nanomaterials are the vehicles which deliver drugs in smaller but equally effective quantities. The aim of this investigation is to synthesize gold nanopartic...

    Authors: M. A. González-López, E. M. Gutiérrez-Cárdenas, C. Sánchez-Cruz, J. F. Hernández-Paz, I. Pérez, J. J. Olivares-Trejo and O. Hernández-González

    Citation: Cancer Nanotechnology 2020 11:4

    Content type: Research

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  20. We previously described the properties of a targeted drug delivery system (DDS) in a cell-free system. Here, in this comparative cell-based study (normal and tumor cells), we provide a quantitative analysis of...

    Authors: Marzenna Wiranowska, Rupin Singh, Rana Falahat, Eva Williams, Joseph O. Johnson and Norma Alcantar

    Citation: Cancer Nanotechnology 2020 11:3

    Content type: Research

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  21. The first-line chemotherapy drug that is used to treat pancreatic ductal adenocarcinoma is gemcitabine. Unfortunately, its effectiveness is hampered by its chemo-resistance, low vascularization and drug biodis...

    Authors: Paweł Nalepa, Robert Gawecki, Grzegorz Szewczyk, Katarzyna Balin, Mateusz Dulski, Mieczysław Sajewicz, Anna Mrozek-Wilczkiewicz, Robert Musioł, Jaroslaw Polanski and Maciej Serda

    Citation: Cancer Nanotechnology 2020 11:2

    Content type: Research

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  22. Fluorescent silica nanoparticles have been extensively utilised in a broad range of biological applications and are facilitated by their predictable, well-understood, flexible chemistry and apparent biocompati...

    Authors: Vladimir Gubala, Giorgia Giovannini, Filip Kunc, Marco P. Monopoli and Colin J. Moore

    Citation: Cancer Nanotechnology 2020 11:1

    Content type: Review

    Published on:

  23. In recent years, disease treatment has evolved strategies that require increase in pharmaceutical agent’s efficacy and selectivity while decreasing their toxicity in normal tissues. These requirements have led...

    Authors: Esteban Beltrán-Gracia, Adolfo López-Camacho, Inocencio Higuera-Ciapara, Jesús B Velázquez-Fernández and Alba A Vallejo-Cardona

    Citation: Cancer Nanotechnology 2019 10:11

    Content type: Review

    Published on:

  24. A wide range of nanoparticles (NPs), composed of different elements and their compounds, are being developed by several groups as possible radiosensitisers, with some already in clinical trials. However, no sy...

    Authors: Alexandra Guerreiro, Nicholas Chatterton, Eleanor M. Crabb and Jon P. Golding

    Citation: Cancer Nanotechnology 2019 10:10

    Content type: Research

    Published on:

  25. Heat generated from plasmonic nanoparticles can be utilized in plasmonic photothermal therapy. A combination of near-infrared laser and plasmonic nanoparticles is compelling for the treatment of brain cancer, ...

    Authors: Yue He, Kristoffer Laugesen, Dana Kamp, Salik A. Sultan, Lene B. Oddershede and Liselotte Jauffred

    Citation: Cancer Nanotechnology 2019 10:8

    Content type: Research

    Published on:

  26. Nanocarriers have the potential to improve the therapeutic index of currently available drugs by increasing drug efficacy, lowering drug toxicity and achieving steady-state therapeutic levels of drugs over an ...

    Authors: Natalia Lemos Chaves, Danilo Aquino Amorim, Cláudio Afonso Pinho Lopes, Irina Estrela-Lopis, Julia Böttner, Aparecido Ribeiro de Souza and Sônia Nair Báo

    Citation: Cancer Nanotechnology 2019 10:7

    Content type: Research

    Published on:

  27. Ion-beam cancer therapy, an alternative to a common radiation therapy with X-rays, has been used clinically around the world since 1990s; the number of proton therapy centers as well as facilities using heavie...

    Authors: Eugene Surdutovich and Andrey V. Solov’yov

    Citation: Cancer Nanotechnology 2019 10:6

    Content type: Review

    Published on:

  28. Relative biological effectiveness (RBE) is a key quantity for the description of radiobiological effects induced by charged-particle irradiation in the context of ion-beam cancer therapy. Since RBE is a comple...

    Authors: Alexey Verkhovtsev, Eugene Surdutovich and Andrey V. Solov’yov

    Citation: Cancer Nanotechnology 2019 10:4

    Content type: Research

    Published on:

  29. This article reviews radiation chemistry processes induced by high-linear energy transfer (LET) radiation. The first part gives a short historical introduction and defines the essential concepts of radiation c...

    Authors: Gérard Baldacchino, Emilie Brun, Ibtihel Denden, Sarah Bouhadoun, Raphael Roux, Hicham Khodja and Cécile Sicard-Roselli

    Citation: Cancer Nanotechnology 2019 10:3

    Content type: Review

    Published on:

  30. Poly(lactic-co-glycolic acid) (PLGA) is a biodegradable and biocompatible polymer which is widely used as a matrix to incorporate therapeutic agents. The anticancer activity of targeted folate-modified docetaxel-...

    Authors: Yuri I. Poltavets, Alexander S. Zhirnik, Vasilisa V. Zavarzina, Yuliya P. Semochkina, Valentina G. Shuvatova, Anna A. Krasheninnikova, Sergey V. Aleshin, Danil O. Dronov, Eugeny A. Vorontsov, Vadim Yu. Balabanyan and Galina A. Posypanova

    Citation: Cancer Nanotechnology 2019 10:2

    Content type: Research

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  31. Radiotherapy is commonly used for treating cancer. Novel sensitizers, such as gold nanoparticles (GNPs), are being used to enhance the local radiation dose. It is not known how the uptake and radiation dose en...

    Authors: Kyle Bromma, Kristy Rieck, Jayesh Kulkarni, Connor O’Sullivan, Wonmo Sung, Pieter Cullis, Jan Schuemann and Devika B. Chithrani

    Citation: Cancer Nanotechnology 2019 10:1

    Content type: Research

    Published on:

  32. Development of biocompatible multifunctional polymeric drug carriers is crucial in modern pharmaceutics aimed to create “smart” drugs. The high potential of the PEGylated comb-like polymeric nanocarrier (PNC) ...

    Authors: Lesya Kobylinska, Igor Patereha, Natalia Finiuk, Natalia Mitina, Anna Riabtseva, Igor Kotsyumbas, Rostyslav Stoika, Alexander Zaichenko and Sandor G. Vari

    Citation: Cancer Nanotechnology 2018 9:11

    Content type: Research

    Published on:

  33. A novel treatment planning framework, the Relative Biological Effective Dose (RBED), for high Z nanoparticle (NP)-enhanced photon radiotherapy is developed and tested in silico for the medical exemplar of neoa...

    Authors: Jeremy M. C. Brown, Gerard G. Hanna, Nathanael Lampe, Balder Villagomez-Bernabe, James R. Nicol, Jonathan A. Coulter and Fred J. Currell

    Citation: Cancer Nanotechnology 2018 9:9

    Content type: Research

    Published on:

  34. C60 fullerene-based nanoformulations are proposed to have a direct toxic effect on tumor cells. Previous investigations demonstrated that C60 fullerene used alone or being conjugated with chemotherapeutic agents ...

    Authors: Larysa M. Skivka, Svitlana V. Prylutska, Mariia P. Rudyk, Nataliia M. Khranovska, Ievgeniia V. Opeida, Vasyl V. Hurmach, Yuriy I. Prylutskyy, Leonid F. Sukhodub and Uwe Ritter

    Citation: Cancer Nanotechnology 2018 9:8

    Content type: Research

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  35. Recently, some studies have focused on dendrimer nanopolymers as a magnetic resonance imaging (MRI) contrast agent or a vehicle for gene and drug delivery. Considering the suitable properties of these material...

    Authors: Marzieh Salimi, Saeed Sarkar, Reza Saber, Hamid Delavari, Ali Mohammad Alizadeh and Hendrik Thijmen Mulder

    Citation: Cancer Nanotechnology 2018 9:7

    Content type: Research

    Published on:

  36. Recent approvals of gene therapies by the FDA and the EMA for treatment of inherited disorders have further opened the door for assessment of nucleic acid pharmaceuticals for clinical usage. Arising from the p...

    Authors: Cian M. McCrudden, John W. McBride, Joanne McCaffrey, Emma M. McErlean, Nicholas J. Dunne, Vicky L. Kett, Jonathan A. Coulter, Tracy Robson and Helen O. McCarthy

    Citation: Cancer Nanotechnology 2018 9:5

    Content type: Research

    Published on:

  37. The combined use of radiation therapy and chemotherapy is commonly being used in cancer treatment. The side effects of the treatment can be further minimized through targeted delivery of anticancer drugs and l...

    Authors: Celina Yang, Kyle Bromma, Caterina Di Ciano-Oliveira, Gaetano Zafarana, Monique van Prooijen and Devika B. Chithrani

    Citation: Cancer Nanotechnology 2018 9:4

    Content type: Research

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  38. Nowadays, viral nanoparticles (VNPs) have attracted a lot of attention, although some are concerned that VNPs may reflect on viral entry of virus into animal or plant cells. In the present study, it aimed to i...

    Authors: Neda Esfandiari, Mohsen Karimi Arzanani and Mina Koohi-Habibi

    Citation: Cancer Nanotechnology 2018 9:1

    Content type: Research

    Published on:

  39. Chemotherapeutic agents have limited efficacy and resistance to them limits today and will limit tomorrow our capabilities of cure. Resistance to treatment with anticancer drugs results from a variety of facto...

    Authors: Eudald Casals, Muriel F. Gusta, Macarena Cobaleda-Siles, Ana Garcia-Sanz and Victor F. Puntes

    Citation: Cancer Nanotechnology 2017 8:7

    Content type: Review

    Published on:

  40. Nanoparticles (NPs) have been shown to have good ability to improve the targeting and delivery of therapeutics. In the field of photodynamic therapy (PDT), this targeting advantage of NPs could help ensure dru...

    Authors: Zahraa Youssef, Régis Vanderesse, Ludovic Colombeau, Francis Baros, Thibault Roques-Carmes, Céline Frochot, Habibah Wahab, Joumana Toufaily, Tayssir Hamieh, Samir Acherar and Amirah Mohd Gazzali

    Citation: Cancer Nanotechnology 2017 8:6

    Content type: Review

    Published on:

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