Skip to main content
Fig. 4 | Cancer Nanotechnology

Fig. 4

From: Evaluation of cytotoxicity and mechanism of apoptosis of doxorubicin using folate-decorated chitosan nanoparticles for targeted delivery to retinoblastoma

Fig. 4

Evaluation of in vitro cytotoxicity by the MTT assay. Different concentrations of doxorubicin were added either as solution or encapsulated in nanoparticles (DOX-CNPs, DOX-CNP-FA) to the wells with medium as control in Y-79 cell line. Medium was changed at 2 days and then every alternate day thereafter with no further dose of the drug added. The extent of growth inhibition was measured at 5 days by the MTT assay. Data as mean ± S.E.M., n = 6. **p < 0.005, DOX in solution versus DOX-CNPs and DOX-CNP-FA. *p < 0.05, DOX in solution versus DOX-CNPs and DOX-CNP-FA (black square—native DOX, black circle—DOX-CNPs, black triangle—DOX-CNP-FA). Void CNPs had no significant toxicity in the Y-79 cell line

Back to article page

Cancer Nanotechnology

ISSN: 1868-6966

Contact us