Toxicogenomics of nanoparticulate delivery of etoposide: potential impact on nanotechnology in retinoblastoma therapy

Table 1 Comparative analysis of encapsulation efficiency, size and zeta potential of etoposide-loaded nanoparticles

PVA (%)	Drug loading (%, w/w)	Organic solvent	Encapsulation efficiency (%)^a	Mean diameter (nm)^b	Zeta potential (mV)^c
2	10	CHCl₃	61	316 ± 1.5	−14 ± 0.9
–	15	–	80	322 ± 1.1	−14 ± 0.9
–	10	CH₂Cl₂	41	299 ± 1.1	−17 ± 1.1
–	15	–	55	305 ± 0.9	−19 ± 1.2
5	10	CHCl₃	60	267 ± 1.2	−20 ± 1.3
–	15	–	86	270 ± 1.0	−19 ± 1.6
–	10	CH₂Cl₂	56	247 ± 1.2	−24 ± 1.8
–	15	–	72	251 ± 1.1	−22 ± 1.2

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